Fri.Oct 21, 2022

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Nuclear Pharmacist by Day, DJ by Night

Pharmacy Is Right For Me

There are so many different types of careers within the field of pharmacy—from research and drug development to pharmacy informatics! To highlight some of the more unique career settings in the industry, we’re introducing a new page on our website— Novel Pharmacy Practice Settings —where you can explore these unique career pathways. In addition to learning more about unique pathways on our new webpage, we’ll also be featuring pharmacists who work in these unique settings on our blog.

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What Impacts Adult Vaccination?

Drug Topics

Adult vaccine uptake lags and understanding the reasons could be important.

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Trending Sources

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Psychedelic Medicine May Offer a Better Solution to Overcoming Alcoholism

Pharmacy Times

The benefits of psychedelic medicine could expand into long-lasting and transformative therapeutics to treat depression better than selective serotonin reuptake inhibitors (SSRIs).

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Vaccine Hesitancy Trends from 2019 to 2022 Evaluated

Drug Topics

As vaccine hesitancy grows, fewer children are receiving routine childhood vaccines.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Experts Discuss the Growing Role of Pharmacy Technicians During COVID-19

Pharmacy Times

In a panel, pharmacy technicians across the world discuss how the role for pharmacy technicians will continue to grow post-pandemic in United States, Portugal, and the United Kingdom.

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Bivalent mRNA COVID-19 Booster Associated With Significantly Higher Antibody Response

Drug Topics

Moderna’s bivalent mRNA COVID-19 booster reached prespecified superiority and noninferiority criteria against multiple strains of SARS-CoV-2.

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More Trending

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Impact of the SARS-CoV-2 Omicron Variant on COVID-19 Reinfection Rates

Drug Topics

The Omicron variant radically changed reinfection rates.

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12 Things Pharmacy Students Can Do to Become Leaders

Pharmacy Times

Small choices during pharmacy school can help students on the path to becoming leaders in the field.

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Patient Advocacy: The Cycle of Paying it Forward

Drug Topics

A look at how a pharmacist's local CPESN network, the Pennsylvania Pharmacists Care Network, and Flip the Pharmacy, helped one pharmacy better serve patients.

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Text message therapy for depression works in young adults

pharmaphorum

Young adults with depression have been treated effectively with a cognitive behavioural therapy (CBT) course – delivered via text message – in a pilot study conducted by researchers in the US. The trial looked at a four-week CBT course adapted from a face-to-face programme to work via text messages, followed by a four-week follow-up period, in around 100 young adults in the US with at least one symptom of moderate depression and no recent history of antidepressant therapy.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Antibiotics Overprescribed to Hospitalized Children with COVID-19

Drug Topics

Although few cultures showed bacterial coinfections, many children were given antibiotics.

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Reexamining the Use of Tacrine for Neurological Diseases

Pharmacy Times

Tacrine was originally brought to the market in 1993 as an acetylcholinesterase inhibitor to fight the symptoms of Alzheimer disease.

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Long COVID Leads to Lingering Effects in Children

Drug Topics

Additional research is needed to fully understand the scope of Long COVID.

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FDA’s vaccines chief sees possibility of more Covid boosters — sooner than he’d like

STAT

Peter Marks, who leads the Food and Drug Administration’s vaccines operation, is still losing sleep over Covid. Yes, vaccines for all age groups have been authorized or approved. Yes, an updated vaccine is now available. And, yes, multiple products are in use and hundreds of millions of doses have been given in this country.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Study: Relaxation of Public Health Interventions for COVID-19 Has Strongest Impact on Children Aged 1 to 4 Years

Pharmacy Times

Researchers suggest that winter 2020 to 2021 public health interventions lowered natural immunity in children and put them at greater risk of respiratory infection after restrictions were lifted.

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Opinion: Support family caregivers to improve and diversify clinical trials

STAT

During the Covid-19 pandemic, America’s 53 million family caregivers gained some long overdue recognition for their vital role as unpaid extenders of an under-resourced health care workforce. The clinical trial enterprise, however, has yet to appreciate caregivers — and fully engage them — as critical partners in recruiting and supporting people who are older, disabled, or have Alzheimer’s disease, cancer, or other chronic medical conditions for research studies.

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Risk of Developing Severe Breakthrough Infection From COVID-19 May Increase Over 50 Years of Age

Pharmacy Times

The risk of severe COVID-19 breakthrough infection was stronger with age and some comorbidities—the findings can inform antiviral distribution to prevent death or respiratory failure.

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STAT+: Inside Michelle McMurry-Heath’s departure from BIO: Firings, internal clashes, and a pivotal job review

STAT

WASHINGTON — Only two years ago, Michelle McMurry-Heath was named chief executive of BIO, the world’s largest biotech trade organization. She was hailed by her predecessor as a “great leader.” So her swift and abrupt exit from the role earlier this month shocked the industry. But it was set in motion in late summer, when the Biotechnology Innovation Organization’s board of directors dispatched an outside firm to produce an “assessment” of her perf

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GSK continues campaign for greater adult immunisation coverage

pharmaphorum

The UK company reveals the results from a partner-led survey to discover the rates of vaccination for adults, why levels are lower than expected, and what can be done to improve this. Ben Hargreaves examines the reasons supplied by the survey and why GSK is invested in the answers. The emergence of COVID-19 meant that public awareness around vaccination and its importance in fighting the spread of infectious disease has increased rapidly.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them.  Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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FDA Accepts New Drug Application for Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy

Pharmacy Times

The treatment modulates the number of myosin heads that can enter “on actin” states and lowers the probability of force-producing (systolic) and residual (diastolic) cross-bridge formation.

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STAT+: Pharmalittle: Pfizer plans to quadruple price of its Covid-19 vaccine; pharma pushed to tie exec compensation to access to meds

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest so far. We plan to tidy up around the castle, visit with the Pharmalot ancestors, and promenade with the official mascot. And what about you? As we have noted previously, this is a fine time to rummage about pumpkin patches and apple orchards, or hop in your motor car to whiz through the countryside and enjo

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Make confident operational decisions by understanding your microflora

European Pharmaceutical Review

The newest revision to regulatory guidance Annex 1 illustrates more stringent contamination control requirements; it is now a regulatory expectation for manufacturers to implement comprehensive and reliable contamination control strategies. Environmental monitoring (EM) programmes can help keep you compliant, measuring the state of control of production and ensuring product safety.

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STAT+: This summer’s Covid surge was bad for hospital profits

STAT

​​This summer’s Covid-19 surge put a sizable dent in hospital finances, with two large investor-owned chains reporting lower revenue and profits in the recently-ended third quarter compared to the same period a year ago. Stocks in HCA Healthcare and Tenet Healthcare shed north of 10% and 30% of their value at times, respectively, on Friday following their underwhelming reports for the quarter, which ended September 30.

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What’s keeping pharma leaders up at night

PharmaVoice

C-suite execs in the life sciences share their late-night thoughts including innovation, patient access and market factors.

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Opinion: Research funding is broken. Using a lottery approach could fix it

STAT

Thirty years ago, Katalin Karikó had what was then an outlandish idea: use messenger RNA as a medicine. But getting funding to demonstrate that might be possible was impossible, despite three decades of trying. One rejection she might now be able to laugh about was a research opportunity with funding for six scientists. It received seven applications — Karikó’s was the only one that wasn’t funded.

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Shingles vaccine offers a decade of protection in older adults

European Pharmaceutical Review

GSK announced Shingrix (Zoster Vaccine Recombinant, Adjuvanted), the first approved shingles vaccine to combine a non-live antigen with a GSK-made adjuvant, can prevent shingles (herpes zoster) for at least decade. Dr Javier Díez-Domingo, Principal Investigator for FISABIO (Foundation for the Promotion of Health and Biomedical Research of the Valencian Community, Spain), explained: “We can now – for the first time – confirm that the clinical benefit of the vaccine continues for at least 10 years

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Study: Adherence to PrEP Increases Prevention of HIV

Pharmacy Times

However, lack of access and awareness about pre-exposure prophylaxis, medication cost, and underestimating disease risk are all barriers to PrEP.

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AbbVie announces acquisition of DJS Antibodies for $255m

Pharmaceutical Technology

AbbVie has announced the acquisition of UK-based biotechnology firm DJS Antibodies for nearly $255m in cash at closing. DJS focuses on the discovery and development of antibody therapies that act on difficult-to-drug disease-causing proteins, such as G protein-coupled receptors (GPCRs). The company leverages its HEPTAD platform to facilitate the antibody discovery of GPCRs and other difficult targets. .

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Gilead and MacroGenics to develop bispecific cancer antibodies

European Pharmaceutical Review

According to a new exclusive option and collaboration agreement between Gilead Sciences, Inc. and MacroGenics, Gilead will use MacroGenics’ DART® platform to develop MGD024, a potential therapy for blood cancers. MGD024 is a bispecific antibody that binds CD123 and CD3, a component designed to reduce CRS, a potentially fatal condition, while enhancing the intensity of antitumour activity with a longer half-life to allow dosing to be intermittent.

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FIP CEO: In Pharmacists’ Emerging Roles, ‘We Need to Deliver What We're Doing Well, Not Wait for Someone's Approval of Our Role’ in Health Care

Pharmacy Times

As a part of the Women in Pharmacy series, Catherine Duggan, FRPharmS, CEO of International Pharmaceutical Federation (FIP), explains her hopes for the pharmacy profession following pharmacists’ pivotal and expanding roles in the pandemic.

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Your endotoxin experts

European Pharmaceutical Review

The future of sustainable Limulus amebocyte lysate (LAL) is here. The launch of Associates of Cape Cod, Inc.’s (ACC) PyroSmart NextGen ® recombinant Cascade Reagent (rCR) marks the introduction of a new sustainable recombinant LAL reagent technology for bacterial endotoxin testing (BET). There are other recombinant reagents on the market, but ACC’s is the only one that uses the same LAL cascade as traditional LAL reagents, while eliminating the potential for 1,3-?

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News Roundup: October 17 to October 21

Drug Topics

Your weekly roundup of the latest news from Drug Topics®.

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Methods for strain comparison and differentiation of environmental isolates

European Pharmaceutical Review

NCIMB Ltd provides microbial identification services and curates The National Collection of Industrial, Food and Marine Bacteria – one of the culture collections that makes up the UK Biological Resource Centre Network. This culture collection dates back to 1950 1 and, given this history, it is no surprise that we occasionally find that a strain within it has been reclassified.

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