Thu.Feb 16, 2023

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Senate hearing to examine bipartisan reforms to rein in middlemen

PhRMA

Did you know that insurance companies use middlemen — known as pharmacy benefit managers (PBMs) — to decide what medicines people can get and what people pay out of pocket for those medicines?

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Phase 3 Data Published for Zavegepant for the Acute Treatment of Migraine in Adults

Drug Topics

Nearly 40 million people in the United States suffer from migraine, with the World Health Organization classifying migraine as 1 of the 10 most disabling medical illnesses.

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Opinion: The haunting brain science of long Covid

STAT

Matt Fitzgerald used to bike up and down 3,500 feet through the Santa Ana Mountains on three-hour rides just for fun. Now, nine months after being infected with SARS-CoV-2, the virus that causes Covid-19, he can’t muster walking on flat surfaces for 20 minutes without days of exhaustion. “My long Covid life remains terrifying,” he told me.

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Mark Cuban Takes on PBMs at Association for Accessible Medicines Annual Meeting

Drug Topics

The founder of Mark Cuban Cost Plus Drug Company called drug pricing "insane" during a fireside chat at the Association of Accessible Medicines annual meeting.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: CRISPR pioneer Feng Zhang launches new genetic delivery startup with $193 million

STAT

Akin Akinc was scouring his email spam box last summer, looking for a missing message, when he stumbled across an unexpected email from a quite recognizable name: Feng Zhang. Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. Since helping to discover CRISPR-Cas9 — often referred to as molecular scissors that can cut into the genome and edit DNA — Zhang has founded at least

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Some States Allowing Donation and Redistribution of Oncology Drugs

Drug Topics

Collections of oncology drugs in 13 states are being redistributed to patients in need.

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GoodPop rolls out oatmilk-based frozen dessert bars

Drug Store News

The fudgy oat milk-based frozen dessert bars are available in four flavors — fudge n’ vanilla crunch, double chocolate fudge, fudge n’ caramel crunch and mint n’ fudge chip.

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Drugs to Watch: 15 Potential Blockbuster Drugs in 2023

Drug Topics

Analysts have identifed treatments that may deliver annual sales topping $1 billion over the next 5 years.

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Senate panel launches effort to shore up health workforce and ease crippling shortages

Fierce Healthcare

Senate panel launches effort to shore up health workforce and ease crippling shortages rking Thu, 02/16/2023 - 16:52

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Researchers link certain genes to obesity complications in women

STAT

With hundreds of genes thought to be linked to obesity, the challenge is sifting through them all to determine which ones increase the risk of downstream complications like heart disease and diabetes. In a study published Thursday in Nature Genetics, researchers took the first steps in finding a potential candidate specifically in women.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Analysis: Medicare Advantage plans more likely to deny inpatient claims

Fierce Healthcare

Analysis: Medicare Advantage plans more likely to deny inpatient claims pminemyer Thu, 02/16/2023 - 14:16

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Medtech starts cutting jobs, Amazon AI researcher jumps to startup, & predicting newborn illness

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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Trial finds care home prescribing pharmacists improve drug burden index

Hospital Pharmacy Europe

The results of a cluster, RCT by UK researchers showed that a care home intervention involving independent pharmacist prescribers was unable to reduce the fall rate among residents over a six month period in comparison to a usual care, but had a significant impact on drug burden index. Older residents in a care home (CH) are recognised as being at a potentially higher risk of medication error and adverse drug reactions due to both polypharmacy and age-related alterations in drug pharmacokinetics

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STAT+: Pharmalittle: New medication appears to stave off type 1 diabetes; CRISPR pioneer founds another startup

STAT

Good morning, and happy Thursday from STAT reporter Andrew Joseph, here filling in for Ed for the day. We’re up and at ‘em on this weirdly warm February day, thanks to today’s cup of stimulation, which promises notes of blueberry and toffee (we’re a light roast, whole milk kind of household). Subtle flavors aside, we’re more focused on the dangerously low levels of beans left in the grinder.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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How to use tretinoin

The Checkup by Singlecare

If you’ve ever researched skin care products that can help reduce wrinkles and fine lines or improve acne, you might have stumbled upon a treatment called tretinoin. Tretinoin is a medication used on the skin that has been shown to aid in certain skin conditions and cosmetic goals. Keep reading to learn more about tretinoin, how it should be used, and safety precautions to keep in mind while using this medication.

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Listen: Vas Narasimhan on the future of pharma, plus Moderna’s vaccine promise & a biotech presidential bid

STAT

Is the pharmaceutical lobby on the ropes? What does it mean when a vaccine is “free”? And does biotech prepare you for the presidency? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Vas Narasimhan, CEO of Novartis and the new chairman of PhRMA, joins us to discuss the industry’s struggles in Washington and whether the deflated biotech sector is still overvalued.

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Adventist Health launches reorganization, lays off 52 administrative employees

Fierce Healthcare

Adventist Health launches reorganization, lays off 52 administrative employees dmuoio Thu, 02/16/2023 - 16:26

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MD Anderson and Xilis partner to expedite new cancer therapies development

Pharmaceutical Technology

The University of Texas MD Anderson Cancer Center has entered a strategic collaboration with biotech company Xilis for advancing new technology and expediting new cancer therapy development. The preclinical research deal will combine the MicroOrganoSphere (MOS) platform of Xilis with the expertise of MD Anderson for advancing new therapies development and cancer research.

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What are the best OTC anti-inflammatory drugs?

The Checkup by Singlecare

Aspirin | Ibuprofen | Naproxen | Diclofenac | Best OTC anti-inflammatories | Side effects | Prescription vs. OTC anti-inflammatories If you experience minor aches and pains, an anti-inflammatory medicine may be the first thing you look for at the pharmacy. There are many different over-the-counter (OTC) drugs that can help relieve inflammation and pain, and they typically fall under the same class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs).

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Dole enters wellness space with fruit-powered vitamins

Drug Store News

The Secret Nature of Fruit supplements uncovers and harnesses the hidden secrets of fruits to deliver key functional nutrients, the company said.

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How to counsel patients on probiotics

The Checkup by Singlecare

The probiotics industry contributes billions of dollars to the U.S. economy each year. With that being said, patients may look to purchase probiotics on their own accord or under the direction of their healthcare provider. Although they’re not usually regulated by the FDA and the guidelines for their use are relatively scarce, probiotics have been shown to have several health benefits.

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New machine-learning tech 'reads and interpret data like a PhD scientist'

Outsourcing Pharma

Scientists can now dramatically reduce trial-and-error experimentation and uncover risks early thanks to an artificial intelligence solutions company.

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Retail sales rebound in January

Drug Store News

Retail sales in January were up 1.5% from December and increased 4.8% year-over-year, according to the National Retail Federation.

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Many patients leave the doctor's office with unanswered questions: survey

Fierce Healthcare

Many patients leave the doctor's office with unanswered questions: survey fdiamond Thu, 02/16/2023 - 08:34

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With their Mist of Wonders spray, DevaCurl is cutting down on product usage

Drug Store News

DSN spoke to Alexis Ansley-Benjamin, director of communications at DevaCurl, about the Mist of Wonders Leave-In Multi-Benefit Curl Spray.

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Ahead of next month's FDA decision, Emergent aces AdComm for over-the-counter Narcan nod

Fierce Pharma

Ahead of next month's FDA decision, Emergent aces AdComm for over-the-counter Narcan nod fkansteiner Thu, 02/16/2023 - 14:12

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RangeMe highlights emerging global buyer trends

Drug Store News

RangeMe's Retail Recap 2022 report finds that coffee, candy and mushrooms were top-of-mind among retail buyers within the last year.

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Patient Metrics Improve With Diabetes App, But Engagement with Physicians May Be Key

Drug Topics

A smartphone app is associated with improvement in HbA1c levels, but physician involvement with patients and other factors may be the benefit.

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Moderna CEO accepts invite to talk vaccine pricing in Congress—just as his company makes access pledge

Fierce Pharma

Moderna CEO accepts invite to talk vaccine pricing in Congress—just as his company makes access pledge fkansteiner Thu, 02/16/2023 - 11:22

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Is 2023 the Year for OTC Naloxone?

The FDA Law Blog

By Kalie E. Richardson — On February 15, 2023, the Nonprescription Drugs Advisory Committee (NDAC) and the Anesthetic and Analgesic Drug Products Advisory Committee (AADPAC) held a joint meeting to discuss an application pending before FDA that would switch Narcan (naloxone) Nasal Spray from prescription to over-the-counter (OTC) status. All 19 members of the joint Advisory Committee agreed that the benefit-risk profile of Narcan Nasal Spray (NNS) is “supportive of its use as a nonprescription

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Aqilion and Merck partner to develop TAK1 protein inhibitors

Pharmaceutical Technology

Aqilion and Merck have entered an exclusive licence and strategic research partnership for the discovery, development and commercialisation of the transforming growth factor-β-activated kinase 1 (TAK1) protein-small molecule inhibitors. Under the deal, Aqilion will receive $10.6m (€10m) in upfront cash payment from Merck and also eligible for up to $1,015m (€950m) in potential development and commercialisation milestone payments, along with tiered royalties on global net sales.

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The Explosive Arrival of Chat GPT and Generative AI

PharmExec

Fran Pollaro talks with Faruk Capan is the CEO, EVERSANA INTOUCH & Chief Innovation Officer, EVERSANA about the arrival of Chat GPT and generative AI in the public consciousness. This is just the beginning.

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Eyenovia and Formosa partner for new ophthalmic therapeutics

Pharmaceutical Technology

Ophthalmic technology firm Eyenovia and Formosa Pharmaceuticals have entered a collaboration agreement to develop new ophthalmic therapeutics. The collaboration will combine the Optejet dispensing technology of Eyenovia with the APNT nanoparticle formulation platform of Formosa to develop topical therapeutics. The Optejet microdose formulation and delivery platform use Microdose Array Print (MAP) technology for delivering 6ml-8ml of the drug.

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Elation adds medical biller Lightning MD with plans to be the sector's first all-in-one technology solution

Fierce Healthcare

Elation adds medical biller Lightning MD with plans to be the sector's first all-in-one technology solution aburky Thu, 02/16/2023 - 12:52

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