Thu.Oct 20, 2022

article thumbnail

Three ways 340B is failing vulnerable patients

PhRMA

The 340B Drug Pricing Program is 30 years old this year, but as The New York Times recently spelled out , the program has become a profit engine for large health systems over the years instead of a program that helps vulnerable, low-income patients. Powerful hospitals have twisted the program to boost their bottom line.

Hospitals 240
article thumbnail

Receipt of Routine Vaccines May Be Predictive of COVID-19 Vaccination Status

Drug Topics

Adults who receive influenza and pneumococcal vaccines may be more likely to receive COVID-19 vaccines and boosters.

Vaccines 195
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Cod Liver Oil Supplementation Not Found to Impact COVID-19 Prevention

Pharmacy Times

Study finds daily supplementation with cod liver oil for 6 months during the SARS-CoV-2 pandemic did not reduce the incidence of SARS-CoV-2 infection.

145
145
article thumbnail

Tackling immune-mediated disease with CAR Tregs

European Pharmaceutical Review

In recent years there has been significant development within the cell therapy field, as chimeric antigen receptor (CAR) T-cell therapy demonstrated an ability to transform the treatment of patients with haematological malignancies. Recognising the potential of CAR T cells to act as highly targeted therapeutics, several biotechnology companies – including Sangamo Therapeutics – have established development pipelines of CAR T regulatory cells (Tregs) that aim to tackle immune?

article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

Expert: Pharmacists Are ‘Very Involved in Holistic Care of Patients With Multiple Myeloma,’ Beyond Treatment Alone

Pharmacy Times

Rachel K. Anderson, PharmD, CSP, clinical program manager at Alliance Rx Walgreens Pharmacy, discusses the impact pharmacists have on the care journey for patients with multiple myeloma.

article thumbnail

Frontiers Health 2022 – day 2

pharmaphorum

And the LIVE coverage continues as we head into Day Two… This day is set to hold even more points of interest, with the demonstration ‘CX innovation: building experiences that work for customers’ (moderated by Healthware Group’s global head of digital strategy and customer engagement Yannick Valenti), as well as the masterclass ‘How to maximise learning science to affect behaviour change’ with Meducate Global’s president, Lawrence Sherman, and MD of Healthware MedComms & SWM, Francis M

116
116

More Trending

article thumbnail

STAT+: As AI grows in medical image analysis, concern about building trust with doctors grows too

STAT

In 2018, the researcher Pranav Rajpurkar was working on an algorithm that could find blood clots in patients’ legs from ultrasound images. It spotted them very well, but when he went looking for what the algorithm had picked up on in the images to make its predictions, he saw it had been cheating: it was looking at the metadata in the top right corner of every ultrasound.

article thumbnail

Pharmacy Focus: Public Health Matters- Celebrating American Pharmacist Month Part 3 with Timothy Gauthier

Pharmacy Times

Staying informed through the right sources and being mindful of antibiotic usage can help health care providers and patients be more prepared for future pandemics.

123
123
article thumbnail

Implications of Current Maternal Tdap Vaccine Uptake on Future Vaccines

Drug Topics

What does the uptake look like for one of the most common vaccines given during pregnancy—and what does this mean for the future?

article thumbnail

Experts Discuss Differences in Role of Pharmacy Technicians in Various Countries

Pharmacy Times

In a panel, pharmacy technicians across the world discuss the differences of the role for pharmacy technicians in United States, Portugal, and the United Kingdom.

120
120
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

U.S. surgeon general says workplaces are taking a toll on Americans’ mental and physical health

STAT

Your job can be hazardous to your health, according to a new report from the U.S. Surgeon General that highlights how the Covid-19 pandemic has revealed fractures in working Americans’ mental health and well-being. Released Thursday, the report cites workplace trends like quiet quitting and the Great Resignation as signals of the damage done to Americans by problems like endless hours, unpaid leave, and chronic stress.

101
101
article thumbnail

Immunotherapy shows benefits for hospitalised COVID-19 patients

European Pharmaceutical Review

Apogenix , a biopharmaceutical company developing next generation immunotherapeutics, announced that asunercept showed statistically significant benefits for hospitalised COVID-19 patients in the ASUNCTIS trial. Apogenix’s lead immunotherapy candidate, asunercept is a fully human fusion protein, consisting of the CD95 receptor and an IgG1 antibody. It is being developed for the treatment of solid tumours, haematological malignancies and viral infections such as COVID-19.

article thumbnail

‘Front of the line’: For Alzheimer’s patients in successful trial, a feeling of gratitude

STAT

When the news came out last month that an experimental Alzheimer’s therapy succeeded in a clinical trial , it provided a rare boost of hope for the millions facing the condition. A select group of patients felt something more: lucky. In interviews, people who participated in the trial and their caregivers described a gratitude at somehow winding up in a study where the drug actually worked, against a backdrop of repeated failures to develop effective Alzheimer’s medications.

101
101
article thumbnail

Examining Factors That Impact Antibiotic Prescribing in Urgent Care

Drug Topics

Determining the characteristics that impact antibiotic prescribing behavior is important for addressing health inequity.

98
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

STAT+: Novartis agrees to license a best-selling cancer drug to dozens of low- and middle-income countries

STAT

Amid a push to widen access to medicines to poor countries, Novartis has reached an agreement to license one of its best-selling cancer treatments so that generic manufacturers can produce copies for distribution to 44 low- and middle-income nations. The deal with the Medicines Patent Pool, a public health organization backed by the United Nations, marks the first time that a voluntary licensing deal has been arranged for a cancer medication.

98
article thumbnail

J&J reveals just how much economic turbulence is affecting Big Pharma

PharmaVoice

The healthcare giant showed pharmaceutical gains, but that's no thanks to the economic environment of persistent inflation and a strong U.S. dollar.

105
105
article thumbnail

Opinion: How states can act to limit drug price increases, saving employers and workers billions

STAT

The Inflation Reduction Act of 2022 mandates that Medicare-covered drug sales will be protected from price increases that exceed inflation, but the mechanics of this “inflation penalty” have generated some confusion. A top Medicare official recently noted that the per-pill value of the Medicare inflation penalty will be calculated based on average prices across both the Medicare and commercial markets, but the penalty will be paid only on prescriptions reimbursed by Medicare.

98
article thumbnail

Achieving commercial excellence with data-driven decisions

pharmaphorum

Executing an effective commercial success strategy requires extensive planning and implementation within pharmaceutical companies that spans teams, functions, and geographies. Together, these groups compile vast amounts of data, including rich information on patient populations, target customers, and the competitive landscape. But after months of effort, in most cases, the usefulness of this data begins and ends in a static slide deck or spreadsheet.

article thumbnail

STAT+: Dozens of institutional investors urge drugmakers to link executive compensation to access to medicines

STAT

Three dozen institutional investors are urging the boards at several of the world’s largest pharmaceutical companies to establish concrete metrics for linking executive compensation with policies that widen access to medicines to low- and middle-income countries. In a series of letters, the investors asked the heads of board compensation committees to examine such steps as voluntary licensing agreements and technology transfer for generic production; supply chain performance for improving

article thumbnail

First patient receives novel, potentially cancer-stopping pill

European Pharmaceutical Review

City of Hope , one of the largest cancer research and treatment organisations in the US, announced that the first patient to receive novel cancer medicine AOH1996, is doing well. The Phase I clinical trial is open at City of Hope Los Angeles. Its objective is to determine the maximum tolerated dose of the investigational pill, AOH1996, and to evaluate the medicine for preliminary efficacy.

96
article thumbnail

BU’s Covid tinkering, FDA on trial, & why it’s hard to take drugs off the market

STAT

What happens when approved drugs turn out not to work? Is it OK to make SARS-CoV-2 hybrids? And are British tabloids reliable sources of science news? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Lawyer and bioethicist ​​Holly Fernandez Lynch joins us to explain a watershed test of the FDA’s authority to revoke drug approvals.

FDA 98
article thumbnail

An Annex 1 and Pharma 4.0 perspective on water quality

European Pharmaceutical Review

An essential part of the manufacturing of drug products is the use of water of different degrees of purity. The US Food and Drug Administration (FDA) defines eight different types of water: non-potable, potable (drinkable), purified, water for injection (WFI), sterile water for injection, sterile water for inhalation, bacteriostatic water for injection and sterile water for irrigation. 1 The last four are produced at separate plants and thus less discussed for pharma since they are unlikely to b

article thumbnail

STAT+: How one pharma insider sees the drug pricing reform law: the impact will ‘vary by product and by company’

STAT

After years of stops and starts, a law was finally passed in Congress this summer to address the rising cost of prescription medicines. The Inflation Reduction Act allows the federal government to negotiate prices for some costly drugs, but only a small number that cost the government the most money. But those medicines can’t have any competing products on the market, and negotiations can’t begin until a small-molecule drug has been available for at least nine years and a biologic

98
article thumbnail

Live from Reuters Pharma 2022 – the pharmaphorum podcast

pharmaphorum

In mid-October, our Web Editor Nicole Raleigh and Deep Dive Editor Eloise McLennan travelled to Nice for the Reuters Pharma event. This special episode includes a conversation recorded on-site with Nicole, Eloise, Virtual Science AI CEO Thomas Hughes, and VSAI VP of global patient affairs Geraldine Reilly. They discuss key takeaways from the event, major trends in the space, and the guests’ work at Virtual Science AI, using technology to help life sciences companies create virtual patient adviso

86
article thumbnail

STAT+: Pharmalittle: Pharma tries to blunt Medicare power to negotiate prices; FDA panel supports withdrawal of premature birth drug

STAT

Top of the morning to you. Another deliciously shiny day is unfolding over the Pharmalot campus, where the skies are blue and a cool breeze is circulating. Although there is much work to be done, please join us as we pause ever so briefly to relish the moment with a tasty cup of stimulation — our choice today is peppermint mocha. After all, life is short, so why not stop to appreciate, yes?

FDA 97
article thumbnail

Species-Specific Transcriptomic Changes During Respiratory Syncytial Virus Infection May Advance Treatment Development

Pharmacy Times

There is currently no approved RSV vaccine despite ongoing research efforts.

Vaccines 122
article thumbnail

How a company aimed at bringing the woolly mammoth back to life spun off a startup that could speed drug development

PharmaVoice

Colossal Biosciences announced the creation of Form Bio — and its “operating system for science” — in September.

98
article thumbnail

First oral combined estetrol contraceptive available in UK

European Pharmaceutical Review

Gedeon Richter has announced that its combined oral contraceptive Drovelis® is the first tablet containing estetrol (E4) and drospirenone (DRSP) to be made available on the NHS in England. The drug (14.2mg estetrol and 3mg drospirenone) is the first oral combined contraceptive containing a new, synthetic natural oestrogen to be offered to patients in the UK.

84
article thumbnail

Latest Research: COVID-19 Vaccines

Drug Topics

A selection of the latest COVID-19 vaccine research out of IDWeek 2022.

article thumbnail

Indonesia bans sale of syrup medicines after at least 99 child deaths

The Guardian - Pharmaceutical Industry

Country investigating 206 cases of kidney injury that could be linked to ingredients in liquid medicines Indonesia has banned the sale of all syrup medicines as it investigates the deaths this year of nearly 100 children, warning that the liquids may contain ingredients linked to fatal kidney injuries. The move comes just weeks after the World Health Organization issued an alert over four Indian-made cough syrups that it said were potentially linked with acute kidney injuries and the deaths of 7

78
article thumbnail

NCPA Urges Department of Defense to Address Pharmacy Access Restrictions for Tricare Beneficiaries

Drug Topics

The new restrictions include both independent and chain pharmacies.

98
article thumbnail

Technicians Perform Vital Role in Academia

Pharmacy Times

Improved workflow and optimal patient outcomes occur when technicians serve as vital members of the health care team, across the continuum of care.

73
article thumbnail

Dan Mack talks blind spots that hinder supplier retail partnerships

Drug Store News

Drug Store News Editor-in-Chief Nigel Maynard talks with Dan Mack about his latest book, "Look Closer: Ideas on Reexamining and Eliminating Personal, Relational, and Organizational Blind Spots.

52
article thumbnail

Sonidegib, a Hedgehog Signaling Pathway Inhibitor for Locally Advanced Basal Cell Carcinoma

Pharmacy Times

Sonidegib binds to and inhibits a transmembrane protein to disrupt hedgehog pathway signal transduction and leading to antitumor activity in patients with locally advanced basal cell carcinoma.

65