Tue.Sep 06, 2022

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Glycemic Control in Teenagers with Type 1 Diabetes Could Be Key to Stave Off Neurological Damage

Drug Topics

Improved glycemic control could reduce the risk of diabetes-related brain damage among teens and adolescents with type 1 diabetes.

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Study: Fertility Preservation Measures Do Not Increase Risk of Breast Cancer Recurrence

Pharmacy Times

Analysis shows that over 5 years, the percentage of women without relapse was 89% for those who had hormonal stimulation of the ovaries and 83% for those with ovarian tissue freezing.

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Pfizer isn’t sharing Covid vaccines with researchers for next-gen studies

STAT

WASHINGTON — Researchers studying next-generation vaccines to fight an evolving Covid-19 threat are running into problems getting existing vaccines to use in their research. Because Pfizer and Moderna hold the patents for the current vaccines, researchers would likely have to get the companies’ permission to use them for research into products like nasal or pan-coronavirus vaccines.

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Migraine, Chronic Migraine Associated with Lower Vitamin B12 Levels

Pharmacy Times

Patients with chronic migraines and higher frequencies of pain experienced the lowest vitamin B12 levels compared with patients with less frequent or no headache symptoms.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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The 2022 PharmaVoice 100

PharmaVoice

From standout executives to R&D pioneers — this year’s class of honorees is defining the next era of leadership.

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CDC Updates ACIP Guidance, Recommending Specific Flu Vaccines for Patients 65 and Older

Pharmacy Times

Flublok Quadrivalent and Fluzone High-Dose Quadrivalent are both proven to prevent more cases in older adults compared with a standard-dose vaccine in randomized controlled trials.

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More Trending

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Study: Better Blood Sugar Control in Teens Limits Diabetes-Related Brain Damage

Pharmacy Times

Cognitive harm appears reversible, results of analysis by Nemours Children’s Health Jacksonville and Stanford University shows.

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Opinion: Open access to research can close gaps for people with disabilities

STAT

In a long-overdue move, the federal Office of Science and Technology Policy has issued guidance on making federally supported research and publications available to all without delay or embargo. This remarkable announcement about open access has the potential to remove information barriers that have long held back social and scientific progress. Even with immediate open access to research results, however, people with disabilities face unique barriers to information access.

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New Data Show Farxiga Lowers Risk of Cardiovascular Death in Patients With Heart Failure

Pharmacy Times

Pre-specified pooled analysis from phase 3 trials demonstrates 14% reduction in CV mortality and from any cause by 10% in individuals with HF, irrespective of ejection fraction.

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NICE says no to Lynparza in prostate cancer, creating UK access divide

pharmaphorum

NICE has said it is unable to recommend NHS use of AstraZeneca’s Lynparza for some patients with prostate cancer, after failing to reach an agreement on price with the drugmaker. The health technology assessment (HTA) authority said that the PARP inhibitor “is not cost-effective at its current price” as a treatment for BRCA-positive prostate cancer that has spread to other parts of the body and relapsed after prior hormonal therapy.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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AHA: Addiction Management Is Key to Treating Heart Infections in Those Who Inject Drugs

Pharmacy Times

A new statement from the American Heart Association stresses withdrawal medications and special care teams to prevent endocarditis in these individuals.

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Pleco raises €17m for tumour microenvironment drug

pharmaphorum

Pleco Therapeutics has closed a first-round financing, raising just over €17 million that it says will fund the development of its lead therapy for acute myeloid leukaemia (AML) through to regulatory filings in the US and EU. The Nijmegen, Netherlands-based biotech was founded in 2018 to develop therapies designed to change the balance of protein expression within the tumour ‘microenvironment’, which can defend cancers against the immune system, and is increasingly becoming a source

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White House signals most people will only need annual Covid booster

STAT

As part of its push to encourage vaccine-weary Americans to get the updated Covid shot, the White House put forth a new selling point Tuesday: to view it as a first annual shot, akin to the annual flu shot. The messaging from the White House — part of a briefing where health officials outlined the rollout of the new bivalent booster shots authorized last week — reflects another transition point in the country’s fight against the coronavirus.

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UK health leaders warn new PM Liz Truss of crisis-in-waiting

pharmaphorum

New UK Prime Minister Liz Truss needs to take immediate action to prevent the NHS spiralling out of control this winter, according to groups representing healthcare workers. Truss takes power as the NHS is in “its worst state in living memory,” according to NHS Confederation chief executive Matthew Taylor, who says it is vital that the health service becomes a “top three” priority for the new administration as it grapples with an estimated real-terms funding cut of £9.4 b

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Opinion: The FDA got it right with hearing aids. Updating Medicare coverage is next

STAT

“You would really benefit from hearing aids, but they aren’t covered by Medicare and cost around $4,000.” We’ve each said this phrase countless times to patients with hearing loss and are prepared for the reaction that invariably follows: an expression of bewilderment about why a pair of hearing aids may have to be their third largest material purchase in life, after a house and car.

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Ocular Adverse Events Linked to Chemotherapies Paclitaxel and Docetaxel

Drug Topics

Patients who received the chemotherapies paclitaxel and docetaxel were at an increased risk of adverse events of the eye.

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What happens to patients when telehealth businesses shutter? 

STAT

Buzzy, venture-backed startups and big tech companies that have promised to disrupt health care are indeed doing so — including by shuttering services that early adopter patients may have come to rely on. Following its deal to acquire primary care tech company One Medical , Amazon announced it was ending its own virtual- and in-person health service Amazon Care , which covers 40,000 patients, by the end of the year.

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4 Easy Strategies to Increase Clinical Revenue for Independent Pharmacies

DiversifyRx

You can reduce your pharmacy’s reliance on PBMs by earning more revenue from clinical services. How is clinical revenue or service-based revenue defined? My definition of clinical revenue has two components: It is revenue that does not flow through a PBM. It leverages your pharmacist’s intellectual knowledge and skills. There are many examples of clinical revenue, such as MTMs, annual wellness visits, LTC consulting, food sensitivity testing, travel vaccines, and more.

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Oscar and his Team!

NF2 BioSolutions

Many of you already know Oscar and his story, but for those who don’t here goes! Oscar is 11, has just embarked on his next chapter starting secondary school. He inherited NF2 from his mum, Jo and was diagnosed about 5 years ago, mainly due to problems he was experiencing in his left foot. So since he got on the merry go round, we know Oscar has bilateral vestibular schwannoma and a frontal lobe meningioma in his head.

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US FDA grants Orphan Drug status to Avacta’s drug for soft tissue sarcoma

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has awarded Orphan Drug Designation (ODD) to Avacta Group’s lead pre|CISION drug candidate, AVA6000, to treat soft tissue sarcoma. Updated using the pre|CISION technology, AVA6000 is a kind of generic chemotherapy doxorubicin. This approach aids the therapy to be activated mainly in the tumour, sparing healthy tissue from exposure.

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Clinical registry data, a valuable source of real-world data

PharmaVoice

Real-world data (RWD) from clinical drug registries can and should be used throughout the drug development lifecycle. At all stages, registries ensure that assumptions about the current standard of care are accurate and evidence-based.

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STAT+: Pharma donations to patient charities may violate the ‘spirit’ of anti-kickback laws

STAT

There is a federal law that prohibits drug companies from directly covering out-of-pocket spending by Medicare beneficiaries. But these companies are allowed to donate to independent charities that provide assistance to patients — and they can earmark donations for a condition treated by their drugs. With this in mind, a group of researchers wanted to know whether the donations are a good investment for the pharmaceutical industry — and they found that, yes, the donations can be pr

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Pfizer bivalent COVID-19 vaccine starts rollout

pharmaphorum

The NHS is moving to the next phase of its SARS-CoV-2 vaccination programme, following health secretary Steve Barclay’s acceptance of advice from the Joint Committee on Vaccination and Immunisation (JCVI) to go ahead with rollout of Pfizer’s bivalent 30mg booster shot this week. The decision follows approval by the Medicines and Healthcare products Regulatory Agency (MHRA) last Saturday, which gave the green light for use of the new vaccine in those aged 12 years and above.

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STAT+: How a tool to map computer viruses came to power biology research

STAT

When mathematicians Leland McInnes and John Healy walked into their work’s annual “Big Dig” — a sort of classified hackathon for Canada’s version of the National Security Agency — in 2017, they were not thinking about biology at all. They wanted to find a way to quickly spot the differences between computer viruses.

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The most important criterion for digital transformation? A change in mindset

Outsourcing Pharma

Bioprocessing 4.0 and digitalization is all about embracing new technologies to enable faster, smoother and more efficient biomanufacturing. And that also requires embracing a new mindset.

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STAT+: Bayer agrees to $40 million settlement over kickbacks and downplaying drug safety risks

STAT

After nearly two decades of litigation, Bayer agreed to pay $40 million to settle a pair of whistleblower lawsuits that accused the company of paying kickbacks to doctors and hospitals, as well as marketing two medicines for unapproved uses and downplaying safety risks of two other drugs. One lawsuit alleged that the company deliberately downplayed risks and overstated benefits of Trasylol, which is used to control bleeding in certain heart surgeries.

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A Strategic Approach to Patient Education Regarding Influenza Vaccine Efficacy

Drug Topics

Expert panelists share their thoughts on how to effectively educate patients on the efficacy of influenza vaccines.

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STAT+: Amazon health feature can accurately assess users’ mobility, study finds

STAT

As Amazon works to shoulder its way into health care, a new study — funded by the company — suggests that a feature of its wearable devices can accurately assess users’ mobility. Last year, Amazon released a movement health feature — included in a subscription membership add-on for the company’s Halo wearable devices — that uses a smartphone camera and app to assess a person’s functional mobility by observing five simple movements, including squat

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7 Tips for Cleaning Your Independent Pharmacy

PioneerRx

There are so many things that go into an independent pharmacy’s success: the quality of patient care, the range (or lack) of clinical services you provide, the.

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Juul to pay nearly $440M to settle states’ teen vaping probe

STAT

HARTFORD, Conn. — Electronic cigarette maker Juul Labs has agreed to pay nearly $440 million to settle a two-year investigation by 33 states into the marketing of its high-nicotine vaping products, which have long been blamed for sparking a national surge in teen vaping. Connecticut Attorney General William Tong announced the deal Tuesday on behalf of the states plus Puerto Rico, which  joined together  in 2020 to probe Juul’s early promotions and claims about the benefit

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Bayer sets out a proposed basis for science-based self-care products

pharmaphorum

The healthcare sector has a “moral imperative” to help people navigate the self-care industry, says pharma giant. Recent years have seen an explosion in the “self-care” industry, a sector that was worth an estimated $4.9 billion in 2019. But in a world of fake news and influencer-led trends, it’s the healthcare sector’s responsibility to ensure people have the knowledge they need to sort the wheat from the chaff.

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Entrepreneurs: Vincent Keunen

PharmaVoice

With his unique platform, the has built a bridge between patients, physicians and researchers around the world.

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STAT+: Pharmalittle: Illumina deal for Grail is blocked after EU veto; CVS buys Signify to expand into house calls

STAT

Good morning, everyone, and nice to see you again after a much-welcomed and extended break thanks, in part, to a holiday on this side of the pond. Now, though, the time has come, once again, to gear up for the usual routine of online meetings, calls, and deadlines. The world, such as it is, continues to spin, no matter how we try to slow it down. So we are succumbing to reality and relying on a few cups of stimulation to cope.

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Anticipating the Prevalence of the Coming Flu Season

Drug Topics

Pharmacist roles are explored as the panel discusses the anticipation of the coming flu season.

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