Sun.Dec 11, 2022

article thumbnail

Four ways Biogen is tackling digital innovation in neurological disease

pharmaphorum

Digital transformation in pharma is not a singular endeavour. It can mean everything from patient-facing disease management apps and wearables to background AI dramatically altering drug discovery or radiological imaging. So, when a life sciences company embarks on a project of digital transformation or innovation, it’s really embarking on multiple projects that span the wide world of pharmaceutical operations.

Hospitals 137
article thumbnail

Expert: Immune Reconstitution With Orca-T Reveals ‘New Realm of Engineered Donor Grafts’ for Patients With Hematologic Malignancies

Pharmacy Times

Expert discusses the results of a trial assessing immune reconstitution in adult patients who received Orca-T, consisting of hematopoietic stem/progenitor cells, regulatory T cells, and conventional T cells.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Urinary Anticholinergics Comparison Table

Med Ed 101

There are a number of medications that can be used for urge urinary incontinence, also known as “overactive bladder syndrome”. However, it can be somewhat difficult to parse out the differences between the medications and decide which might be the right choice for a patient. Today, we’ll be taking a closer look at the urinary […]. The post Urinary Anticholinergics Comparison Table appeared first on Med Ed 101.

105
105
article thumbnail

STAT+: Argenx antibody drug benefits patients with platelet-destroying autoimmune disorder

STAT

NEW ORLEANS — An antibody treatment developed by the Belgian drugmaker Argenx raised platelet counts and stopped bleeding episodes in patients with a rare autoimmune disorder that causes the body to attack and destroy its own blood-clotting platelets. The clinical trial results represent a potentially new and more effective way of treating adults with primary immune thrombocytopenia (ITP), a debilitating condition that, when severe and uncontrolled, can force patients to have their spleen

article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

What key trends will emerge in the retail sector in 2023?

Drug Store News

A new white paper from Placer.ai identifies ​​​​​​nine key trends that may play an important role in the retail sector in 2023.

111
111
article thumbnail

Strep A home-test kits sell out after spate of UK deaths sparks panic buying

The Guardian - Pharmaceutical Industry

Pharmacists also report difficulties finding supplies of antibiotics to treat the infection Strep A home-testing kits have sold out online as parents rush to find ways to diagnose their children’s rashes and high temperatures. The panic-buying follows the deaths of at least 16 children from invasive strep A infections in the UK, with the latest fatality involving a secondary school pupil at Hove Park school in Hove on Friday.

89

More Trending

article thumbnail

Phase 3 Trial Results Show Metabolic Tumor Volume Improves Prognostication Compared With SPD in Second-Line R/R LBCL

Pharmacy Times

Expert discusses clinical outcomes of the phase 3 ZUMA-7 trial assessing axicabtagene ciloleucel versus standard-of-care in second-line large B-cell lymphoma by metabolic tumor volume.

65
article thumbnail

Bel Brands USA intros plant-based Nurishh, The Laughing Cow options

Drug Store News

New launches include Nurishh Incredible Dairy Animal Free Cream Cheese Spread Alternative and The Laughing Cow Plant-Based

98
article thumbnail

Second-Line Polatuzumab Vedotin Plus R-ICE in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Produces High ORR

Pharmacy Times

Expert discusses the safety and efficacy of polatuzumab vedotin combined with rituximab, ifosfamide, carboplatin, and etoposide (R-ICE) as second-line treatment in a multicenter phase 2 study.

65
article thumbnail

HRG’s five notable products from November 2022

Drug Store News

For the month of November, suppliers introduced 249 products, which is almost double the amount they introduced in October.

97
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

Expert: Phase 3 MEDALIST Trial Results Show ‘Red Blood Cell Transfusion Independence for Substantial Period of Time’ in LR-MDS

Pharmacy Times

Expert discusses the effect of baseline transfusion burden and luspatercept dose level on response to treatment in patients with LR-MDS from the MEDALIST study.

65
article thumbnail

Food Lion expands pickup service to 25 additional stores

Drug Store News

Food Lion now offers Food Lion to Go pickup or home delivery at 86% of its 10-state operating area.

98
article thumbnail

#ASH22: Pirtobrutinib emerges as an option for Richter’s Transformation

Pharmaceutical Technology

Richter’s transformation (RT) is a rare blood cancer arising in up to 10% of patients with chronic lymphocytic leukemia (CLL) and presenting as aggressive lymphoma, typically as diffuse large B-cell lymphoma (DLBCL). Due to the rarity of the disease, no FDA-approved therapy exists specifically for RT, and these patients are treated using regimens derived from the DLBCL treatment paradigm and other small-scale clinical trials.

article thumbnail

CVS Health’s Aetna donates $9.3M to fund behavioral, social care needs of youths

Drug Store News

The funding will support community-based organizations providing CSED waiver services.

98
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Medical marijuana decreases opiate use in patients with cancer

Hospital Pharmacy Europe

Medical marijuana has been found to be associated with a reduced use of opiates among patients with breast, colorectal and lung cancer. With greater state medical marijuana legalisation in the US, researchers have found a lower rate of opioid dispensing and pain-related hospital events among some adults receiving treatment for newly diagnosed cancer.

article thumbnail

#ASH22: Frontline Imbruvica threatens transplant use in a MCL patient subset

Pharmaceutical Technology

Mantle cell lymphoma (MCL) is a type of B-cell non-Hodgkin’s lymphoma (B-NHL), typically aggressive but often with an indolent presentation. For young patients with MCL, the standard of care (SOC) is a rituximab-based chemotherapy regimen such as R-CHOP/DHAP, followed by an autologous stem cell transplant (ASCT). BTK inhibitors such as AbbVie’s /Janssen’s Imbruvica (ibrutinib) are SOC for relapsed/refractory (R/R) MCL patients, and previous data from the Phase III SHINE study in older MCL patien

article thumbnail

Increased cholinesterase activity associated with delirium during critical illness

Hospital Pharmacy Europe

A higher cholinesterase activity in critically ill patients increases the risk of delirium but does not lead to cognitive impairment over time. Elevated activity of the cholinesterase enzyme, acetylcholinesterase in critically ill patients is associated with a greater risk of being delirious but fortunately, does lead to subsequent cognitive impairment following discharge from hospital according to the findings of a prospective study by US researchers.

article thumbnail

Fresenius Kabi intros generic Folotyn

Drug Store News

Generic Folotyn is used to treat adult patients with relapsed or refractory peripheral T-cell lymphoma.

64
article thumbnail

Highly purified EPA decreases adverse cardiovascular events in patients with CAD

Hospital Pharmacy Europe

A purified EPA formulation lowered adverse cardiovascular events in those with coronary artery disease (CAD) compared to a control group. The use of a highly purified eicosapentaenoic acid (EPA) formulation in patients with coronary artery disease concurrently taking statins, reduced the incidence of adverse cardiovascular outcomes such as myocardial infarction and stroke compared to a control group not taking the formulation, according to the findings of a study by Japanese researchers presente

article thumbnail

CAR-T Cell Therapies: Advancing Immune Cells to Treat Cancer

Roots Analysis

Cancer is known to be one of the leading causes of deaths worldwide. In fact, as per the WHO, close to 10 million cancer related deaths were reported in 2020. Further, it is estimated that, by the end of 2040, 27.5 million new cancer cases will be added to the global numbers , exerting tremendous physical, emotional and financial strain on affected individuals, their families, communities and national health systems.

article thumbnail

PCSK9 inhibitor persistence high in patients with FH

Hospital Pharmacy Europe

PCSK9 inhibitor persistence in patients with familial hypercholesterolaemia is high and linked with an improvement in LDL-C goal achievement. In clinical practice, persistence with PCSK9 inhibitor therapy in patients with familial hypercholesterolaemia (FH) over time is very high and associated with achievement of low-density lipoprotein cholesterol (LDL-C) goals as well as an improvement in quality-of-life according to an analysis of clinical practice data by Spanish researchers.

article thumbnail

Antibody Drug Conjugates Market: The Future of Novel Therapies

Roots Analysis

Antibody drug conjugates (ADCs) are an upcoming class of targeted therapeutic agents that have garnered the attention of pharmaceutical companies, and academic / research institutions across the world. Fundamentally, these complex biotherapeutic entities represent the combination of the target specificity of an antibody and the therapeutic features of a chemotherapy / cytotoxic drug.

article thumbnail

US FDA grants Fast Track status for Pfizer-BioNTech’s combination vaccine

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted Fast Track designation for Pfizer and BioNTech’s messenger ribonucleic acid (mRNA)-based combination vaccine candidate against Covid-19 and influenza. The vaccine is intended to prevent two respiratory ailments through a single injection. In November, the companies announced plans for a Phase I clinical trial of the combined vaccine candidate in healthy adult subjects.

Vaccines 115
article thumbnail

T-Cell Immunotherapies Market: A New Paradigm in Cancer Treatment

Roots Analysis

Cancer is one of the leading causes of mortality, accounting for 0.6 million deaths in 2021, in the US alone. As per the International Agency for Research on Cancer (IARC), by 2040, there are likely to be 27.5 million new cases and 16.3 million deaths related to cancer, annually. Although cancer therapeutics continue to be one of the most active areas, in terms of drug development, there is still a significant unmet need in this domain.

article thumbnail

STAT+: Novartis develops CAR-T therapy that can be made in a fraction of the standard time

STAT

NEW ORLEANS — For some patients suffering with certain blood cancers, CAR-T therapy can offer the tantalizing chance to end their disease with a single treatment. But the immunotherapy takes time to manufacture, and patients often have to wait weeks to actually receive an infusion once they’re eligible. For some patients with especially aggressive cancer, they can die while waiting for the therapy to arrive.

95