Fri.Jul 08, 2022

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Expert: FDA Announcement of Pharmacists’ Prescribing Authority for COVID-19 Antiviral Paxlovid ‘Is Pharmacy’s Moment’ to Seize the Path to Provider Status

Pharmacy Times

David Pope, PharmD, CDE, the EVP of Innovation and Industry Relations at OmniSYS, discusses the FDA’s announcement updating pharmacists’ prescriptive authority for the COVID-19 antiviral Paxlovid.

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Pharma’s spend on AI in drug discovery ‘could top $3bn by 2025’

pharmaphorum

The pharmaceutical industry is increasingly relying on artificial intelligence to power its drug discovery and development efforts, and its spend in this area has created a multibillion-dollar market for AI technologies. That’s the conclusion of a GlobalData report , which notes that AI is being used to enhance computer-aided drug design (CADD) in a bid to reduce the time and costs involved in getting a new drug to market.

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Vitamin D Intoxication from Supplements Both Possible and Harmful, Physicians Report

Pharmacy Times

Hypervitaminosis D, a condition characterized by elevated vitamin D levels, is associated with potential serious health issues, such as psychosis, abdominal pain, vomiting, pancreatitis, and renal failure.

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Microbial risks presented by aging facilities

European Pharmaceutical Review

As established facilities age, various risk considerations emerge. While some may continue to function effectively without any additional considerations, many will require additional checks and assessment. In an article published in the Journal of Validation Technology (JVT), pharmaceutical microbiologist and contamination control expert Tim Sandle identified ten categories of risk presented by aging.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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ProAir Digihaler Shows Promise Treating Poorly Controlled Asthma

Pharmacy Times

ProAir Digihaler Inhalation Powder is indicated for the treatment or prevention of bronchospasm in those with reversible obstructive airway disease and for the prevention of exercise-induced bronchospasm.

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Specialised Therapeutics’ breast cancer drug gets Philippines FDA approval

Pharmaceutical Technology

Specialised Therapeutics’ oral drug, Nerlynx (neratinib) has obtained the Philippines Food and Drug Administration approval to lower the recurrence or mortality risk in early-stage HER2-positive (HER2+) breast cancer patients. The treatment is indicated as extended adjuvant treatment for adults with early-stage HER2-overexpressed/amplified breast cancer following adjuvant trastuzumab-based therapy.

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Digital tools driving innovative clinical trials

pharmaphorum

The COVID-19 pandemic has catalysed significant changes in the way pharma develops drugs, particularly in the clinical trial space. Hybrid or decentralised clinical trials (DCTs) have gained traction as technology, infrastructure and knowledge have evolved to support their use. Preliminary research suggests that hybrid DCTs can reduce trial timing and resources , improve patient-centricity and patient engagement , and expand access and recruitment and increase diversity , mitigate bias, and re

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Analysis Finds Mantle Cell Lymphoma Treatment Varies by Clinical Setting

Pharmacy Times

Autologous stem cell transplantation was underutilized in community settings for mantle cell lymphoma.

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Breaking Down Barriers

PharmExec

Dealing with discrimination and bias throughout her career, Otsuka Pharmaceutical’s Christine Sakdalan has forged a strong leadership path built around a two-pronged mission—finding true meaning in the patient journey through market research and data analytics, and mentoring and supporting the development of today’s aspiring professionals.

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Keynote Speaker at McKesson ideaShare 2022 Urges Pharmacists to Care for Themselves, Consider the Future

Pharmacy Times

Simple changes to each day can improve motivation and wellness for pharmacists.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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A Steadying Force in C-Suite: The Changing Role of Biopharma CFOs

PharmExec

COVID-19 pandemic, the challenging capital-markets climate in biotech, and a more innovative and specialty treatment focus has increased reliance on the finance arm as a key strategic cog.

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Expert: Understanding Cardio-Oncology Is Critically Important to Address the High Rate of Heart Disease in Patients With Cancer

Pharmacy Times

Christopher Fine, MD, FACC, a cardiologist at National Jewish Health, discusses the relationship between heart disease and cancer and the importance of the field of cardio-oncology when treating patients with cancer.

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Sobi enters licence agreement for ADC’s Zynlonta

Pharmaceutical Technology

Swedish Orphan Biovitrum AB (Sobi) has signed an exclusive licence agreement with ADC Therapeutics to develop and market Zynlonta (loncastuximab tesirine) for hematologic and solid tumour indications in Europe and mostinternational markets, for up to $435m. The deal, however, excludes the US, Greater China, Singapore and Japan. Zynlonta is a CD19-directed antibody-drug conjugate (ADC).

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Daily Medication Pearl: Tildrakizumab-asmn (Ilumya)

Pharmacy Times

Tildrakizumab-asmn (Ilumya) is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Addressing Rising Rx Costs

Pharmaceutical Commerce

How did the industry get here and what alternatives can be sought out?

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New Diabetes-Related Statistics in the United States

Pharmacy Times

In February of this year, the new statistics came out where we're at now 37 million with diabetes and 96 million with prediabetes.

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Asia’s Rise in The Global Pharma Industry

PharmExec

Continent has shed its ‘emerging’ status on world biopharma stage.

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Expert: ‘Our Understanding of Homologous Recombination Deficiency Is Evolving’ in Oncology Pharmacy Field

Pharmacy Times

Christine Walko, PharmD, BCOP, FCCP, discusses some new developments for PARP inhibitors in cancer care for patients with homologous recombination deficiency.

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AstraZeneca acquires TeneoTwo in $1.3bn deal to broaden haematology portfolio

Pharmaceutical Technology

Over recent years, bispecific T-cell engagers (BiTEs) have attracted significant attention for their potential in treating a plethora of haematological and solid tumours by enhancing the anti-tumour responses of endogenous T-cells. BiTEs are a relatively nascent modality and have yet to benefit from the identification of robust biomarkers and novel combination approaches, such as in combination with anti-CD20 therapies, with the view to attenuate malignant B-cell survival and enhance clinical re

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Utilizing the Pharmacist Patient Care Process as a Pharmacy Team Member

Pharmacy Times

The Pharmacist Patient Care Process provides really consistent language for pharmacists and pharmacy team members to talk about what teams are already doing.

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Europe is seeing a hiring boom in pharmaceutical industry cloud roles

Pharmaceutical Technology

Europe was the fastest growing region for cloud hiring among pharmaceutical industry companies in the three months ending April. The number of roles in Europe made up 16.2% of total cloud jobs - up from 13.6% in the same quarter last year. That was followed by North America, which saw a 0.3 year-on-year percentage point change in cloud roles. The figures are compiled by GlobalData, who track the number of new job postings from key companies in various sectors over time.

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Dynamic Compliance: The Best Defense for Pharma

PharmExec

A proactive and tailored compliance department—with the nimbleness to adapt strategies on the fly—is a critical shield for life sciences companies during government investigations.

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The pharma industry found it harder to fill digitalization vacancies in Q1 2022

Pharmaceutical Technology

Digitalization related jobs that were closed during Q1 2022 had been online for an average of 34 days when they were taken offline. This was an increase compared to the equivalent figure a year earlier, indicating that the required skillset for these roles has become harder to find in the past year. Digitalization is one of the topics that GlobalData, our parent company and from whom the data for this article is taken, have identified as being a key disruptive technology force facing companies i

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The 2022 BoardVitals Medical School Scholarship Winners 

Board Vitals - Pharmacist

Failure is a part of life, even in healthcare. While mistakes will inevitably happen, we must learn from these errors in order to have a greater chance of success in the future. As part of a commitment to supporting the doctors of the future, BoardVitals awarded its third annual Medical School Scholarship to three winners. For the 2022 BoardVitals Medical School Scholarship , we asked current medical students to answer the question: “What have you learned from previous failures and how have thes

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Xenetic Biosciences and Catalent sign deal for cGMP manufacturing

Pharmaceutical Technology

Xenetic Biosciences and Catalent Pharma Solutions have signed an agreement for the cGMP manufacturing of the Xenetic’s recombinant protein, Human DNase I. Under the deal, Catalent will use its biomanufacturing capabilities in Madison, Wisconsin to advance Xenetic’s DNase clinical development programme and progress it to first-in-human studies. The interventional DNase based oncology platform of Xenetic is intended to boost outcomes of current therapies, including immunotherapies.

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Part B reimbursement: earn revenue while saving time

PharmD Live

Burnout can keep the best from wanting to open the doctor’s office each day. A national survey, The Physician Task Load and the Risk of Burnout Among US Physicians ( The Joint Commission Journal on Quality and Patient Safety 2021; 47:76–85 ), describes the look and feel of an albatross around the necks of struggling providers. The metaphor is supported by the direct relationship between physician task load and burnout.

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Teaching the basics of health technology assessment

NICE

The course is made up of six learning modules and can be found on the EHDEN Academy website. The EHDEN Academy is a free learning resource, focusing on providing the knowledge, skills, and tools to access and use real-world evidence. Innovative medical technologies and devices are increasingly important in delivering positive health outcomes and driving health efficiencies.

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Nordstrom Anniversary Sale Picks 2022

The Luxe Pharmacist

I am a huge sucker for a sale, especially when it’s at one of my favorite stores! I mean why buy boots two months from now when you can buy them this week for like $70 less right?! I’m linking all my favorite sales pics here and will be uploading more on my LTK so be sure to follow me there!

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In DOJ Crosshairs: Rethinking Commission-Based Deals With Independent Contractors

PharmExec

Pharma companies should review their commission-based compensation arrangements with independent contractors to address enforcement risk under the Anti-Kickback Statute, in light of recent Department of Justice enforcement.

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Deals relating to regenerative medicine decreased significantly in the pharmaceutical industry in H1 2022

Pharmaceutical Technology

In the first half of 2022 the number of deals relating to regenerative medicine decreased significantly by 40% from the same period in 2021. This marks a deceleration in growth from the 27.6% decrease in deals that occurred in H2 2021 relative to the same period a year earlier. GlobalData's deals database looks at mergers, acquisitions and venture capital and private equity investments taking place daily between thousands of companies across the world.

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Sobi bolsters blood division via $435m ADC licensing deal

pharmaphorum

Swedish rare disease specialist Sobi is paying $55 million upfront to license rights to ADC Therapeutics’ lymphoma therapy Zynlonta – approved in the US last year – in Europe and other international markets. The deal expands Sobi’s position in orphan diseases within haematology, one of its core focus areas, and also includes a $50 million payment Zynlonta (loncastuximab tesirine) is approved in the EU and another $330 million in milestone payments tied to other regulatory and sales o

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Aligning AB’s Services and Solutions: Willis Chandler

Pharmaceutical Commerce

Willis Chandler, AmerisourceBergen’s recently named President of Biopharma Services, Strategic Global Sourcing and Commercial Solutions, talks about the new investments AB is making to build out its capabilities and its new cell and gene therapy service line.

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PharmStars Announces “Innovations in Real-World Evidence” Theme for Fall 2022 Accelerator

pharmaphorum

PharmStars , the pharma-focused accelerator for digital health startups, is pleased to announce that it is now accepting applications for its Fall 2022 cohort with the theme, “Innovations in Real-World Evidence.”. Data gathered from wearables, mobile devices, and other digital tools can yield reliable, usable clinical and health-related information as well as evidence.

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Cracking Down on Speaker Programs

PharmExec

With heightened government scrutiny on educational forums, biopharma manufacturers need a sound framework that demonstrates they are following best practices.

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