Wed.Aug 03, 2022

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ICYMI: Patients across the country are sharing concerns about government price setting

PhRMA

As members of Congress continue to push forward misguided government price-setting policies under the guise of “negotiation,” patient advocates across the country have been speaking out in local media outlets about the potential consequences.

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Resistant Starch in Foods Can Reduce Hereditary Cancer by 50%

Pharmacy Times

Findings in a new trial show that dietary supplementation of resistant starch has the potential to decrease people’s risk of certain types of gastrointestinal cancers.

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The Senate’s latest price setting proposal will undermine U.S. economic growth

PhRMA

Last week, we examined ways the latest drug pricing proposal will undermine patient access to medicines , American medical innovation and our health care system as a whole. But there is another consequence that we can’t leave out: the impact this proposal will have on the biopharmaceutical industry’s contributions to American jobs and the economy.

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Staying Grounded, Finding Support is Essential to Combating Imposter Syndrome

Pharmacy Times

As leaders, we should ask ourselves if any of our people might feel imposter syndrome and what can we do to calm their anxiety and boost their confidence.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Connecting EHR to clinical trials: How to embrace the promise of real-world data

pharmaphorum

We all know that real-world data (RWD) from electronic health records (EHR) could boost clinical trial efficiency and improve patient outcomes – so what’s holding us back? It’s been more than two decades since the ground-breaking potential of using electronic health records (EHR) to inform clinical research was first mooted. Since then, progress has been slow, but the industry now has everything it needs to close the feedback loop between science, evidence, and care, said speakers at a recent Co

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Study: Population Immunity More Important for Controlling Transmission of COVID-19 Than Individual Vaccination Status

Pharmacy Times

Increasing population immunity decreased transmission of COVID-19 and allowed for reductions in quarantine and testing, encouraging 2-dose vaccine and booster uptake.

More Trending

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Clinical Overview: Pharmacist Intervention for Patients on Cardiovascular Drugs

Pharmacy Times

Pharmacist interventions can provide patient-specific guidance to identify and solve problems with medication regimens to ensure optimal outcomes.

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Roche adds to pipeline with Poseida, Kiniksa deals

pharmaphorum

Roche has announced a pair of licensing deals with Poseida Therapeutics and Kiniksa Pharmaceuticals that bolster its pipeline in cancer and inflammatory diseases. The agreement with Poseida is by far the larger of the two, with Roche paying $110 million upfront to license rights to off-the-shelf CAR-T therapies aimed at haematological cancers, including one targeting BCMA on phase 1 testing and another targeting CD19 and CD20 that is due to start trials in 2023 – known as the tier 1 candidates.

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Biktarvy Demonstrates High Efficacy for Broad Range of Patients Initiating Treatment for HIV

Pharmacy Times

Participants who initiated treatment with Biktarvy demonstrated superior hepatitis B virus (HBV) DNA suppression and HBV e-antigen seroconversion.

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Pharmacopoeias to further support vaccine development and supply

European Pharmaceutical Review

Ph. Eur. The European Pharmacopoeia (Ph. Eur.) Commission has established the mRNAVAC Working Party to begin working on quality standards to support the emerging field of messenger RNA (mRNA) vaccines. The newly created Working Party’s first task will be to develop a consolidated strategy for future standards addressing these vaccines and their components.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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A Primer for Medical Specialty Drug Utilization Management Strategies

Pharmacy Times

Case management programs or pharmacist-delivered high-touch care are critical components in medical specialty drug management.

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Editas, Real Chemistry and Compass blaze new trails with pivotal C-suite hires

PharmaVoice

How these latest executive personnel changes are impacting the industry.

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Tip of the Week: Use Mindfulness To Be An Effective Leader

Pharmacy Times

Effective pharmacy managers help everyone to see the proverbial forest through the trees.

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Chinese biotech Sironax raises $200m for RIPK1 pipeline

pharmaphorum

Beijing biotech Sironax has closed a whopping $200 million second-round financing that shows investors still have a desire to back companies working on RIPK1 inhibitors despite setbacks for GSK in the class. The five-year-old Chinese company – which is developing drugs for age-related degenerative diseases – said it will use the proceeds of the Series B to support the clinical development of its RIPK1 inhibitors as well as to expand its pipeline of drug candidates in other classes.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pfizer, BioNTech Initiate Phase 2 Study of Enhanced COVID-19 mRNA-Based Vaccine

Pharmacy Times

The next-generation vaccine candidate, BNT162b5, consists of RNAs encoding enhanced prefusion spike proteins for the SARS-CoV-2 ancestral strain and an Omicron variant.

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Rigel and Forma enter licence deal for acute myeloid leukaemia therapy

Pharmaceutical Technology

Rigel Pharmaceuticals has signed a licence agreement with Forma Therapeutics for developing, producing and marketing olutasidenib to potentially treat relapsed/refractory acute myeloid leukaemia (R/R AML) and other types of cancer. . Olutasidenib, an investigational agent, is an oral, small molecule inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1) that attaches to and hinders mutated IDH1 enzymes.

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FDA Approves Ranibizumab-eqrn Biosimilar, Interchangeable with Lucentis

Pharmacy Times

Ranibizumab-eqrn is the only biosimilar approved for all 5 Lucentis indications.

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HERBAL / NATURAL INGREDIENTS FOR SKIN NOURISHMENT FROM A TO Z

Pharma Tutor

HERBAL / NATURAL INGREDIENTS FOR SKIN NOURISHMENT FROM A TO Z. About Authors. Avdesh Thassu. MPharm (Nat. Chem.); MBA(Mkt.). admin. Wed, 08/03/2022 - 15:44. Tags. Articles.

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T-cells First Protect Against but then Promote Growth of Colorectal Cancer Tumors, Study Finds

Pharmacy Times

Gamma-delta T-cells undergo a biochemical change that leads them to spur the growth of tumors that previously restricted.

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Getting Started as a Medical Writer for Pharmacists in the United States and Canada

The Happy PharmD

Getting Started as a Medical Writer for Pharmacists in the United States and Canada. In this special webinar session , I had the pleasure of teaming up with one of the coaches at the Happy PharmD, Janan Sawar, to host our guests Milena Murray, June Stevens, and Warda Nawaz discuss how pharmacists can transition into medical writing. . Brief Background on our guests.

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Genentech’s Subcutaneous Tecentriq Demonstrates Positive Phase 3 Results for NSCLC

Pharmacy Times

IMscin001 analysis shows non-inferior levels of the cancer immunotherapy in the blood compared with intravenous infusion in individuals with advanced non–small cell lung cancer.

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Phase 3 lung cancer fail dents prospects of Ipsen, Servier’s Onivyde

pharmaphorum

Ipsen and Servier’s hopes of extending the uses for chemotherapy drug Onivyde have been knocked back by a failed phase 3 trial of the drug as a second-line therapy for small cell lung cancer (SCLC). In the RESILIENT study, Onivyde – a liposomal formulation of the well-established cytotoxic drug irinotecan – was unable to improve overall survival when used as a monotherapy after first-line platinum chemotherapy for SCLC, when compared to generic therapy topotecan.

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Daily Medication Pearl: Ezetimibe (Zetia)

Pharmacy Times

Ezetimibe (Zetia) is an inhibitor of intestinal cholesterol and related phytosterol absorption indicated as an adjunct to diet to reduce elevated total cholesterol.

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Gilead reports 1% rise in revenue for Q2 2022

Pharmaceutical Technology

Gilead Sciences has reported a 1% growth in revenue to $6.3bn in the second quarter (Q2) of 2022 as against $6.2bn in the year-ago quarter. The company attributed the revenue rise to enhanced sales in HIV and oncology products, which was offset partially by reduced sales of Veklury (remdesivir) and hepatitis C virus (HCV) medicines. For the three months ended on 30 June 2022, diluted earnings per share (EPS) declined to $0.91 from $1.21 in Q2 2021.

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Daily OTC Pearl: Dermala

Pharmacy Times

Dermala helps support hormonal balance, which may help in the treatment of acne.

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Internet of things hiring levels in the pharmaceutical industry rose in July 2022

Pharmaceutical Technology

The proportion of pharmaceutical companies hiring for internet of things related positions rose in July 2022 compared with the equivalent month last year, with 18.2% of the companies included in our analysis recruiting for at least one such position. This latest figure was higher than the 14.6% of companies who were hiring for internet of things related jobs a year ago but a decrease compared to the figure of 19.7% in June 2022.

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Payers Believe Lowering Drug Prices While Improving Patient Access Is Possible—but There’s a Catch

PharmExec

Value-based price for access (VBPA) may increase access of specialty drugs for patients.

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Woman of the Week: Alloy Therapeutics’ Heather Schwoebel

PharmaVoice

The CBO and COO is leaning on her experience navigating the unknown to turn Alloy into an innovation multiplier.

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June Air Freight Stats Support Resiliency, IATA Says

Pharmaceutical Commerce

Association’s director general recommends air cargo developments be closely monitored in second half of year.

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Estrogen Dosing With Oral Contraceptives

Med Ed 101

Estrogen dosing with oral contraceptives can be a challenging issue that may feel overwhelming to many clinicians. The most common synthetic estrogen analog is ethinyl estradiol. In this article, I’ll discuss the reasons why we might select one dose of estrogen over another. Ethinyl estradiol dosing in oral contraceptives can vary significantly.

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The radiopharmaceuticals vision — and the next-gen companies seeing it through

Pharma Manufacturing

Modern radiopharmaceutical companies are stacked with experienced experts who are laser-focused on correcting the missteps and misfortunes of earlier pioneers

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Q&A with Dr. Kyle Flanigan, Ph.D., Co-Founder and CEO of USSF

PharmExec

Dr. Kyle Flanigan, Ph.D., discusses the benefits of an oral COVID-19 vaccine.

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New life sciences development destined for Paddington

Pharma Times

The sites will maximise local and global benefits of NHS, research, industry and community partnerships

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Oregon Freeze Dry Opens $7.5 Million Biopharma Facility

Pharmaceutical Commerce

New facility will provide lyophilization services.

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