Tue.Jul 12, 2022

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Pharmacy Focus: On The Shelf - Managing Burnout, Mental Health

Pharmacy Times

On this week's episode, Joanna speaks with Carlene Link, PharmD, a clinical pharmacist and integrative life coach, about burnout, managing mental health, and the state of pharmacy.

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Vertex signs agreement to acquire ViaCyte for $320m

Pharmaceutical Technology

Vertex Pharmaceuticals has signed a definitive agreement for the acquisition of biotechnology company ViaCyte in a deal totalling $320m in cash. ViaCyte focuses on offering new stem cell-derived cell replacement therapies as a functional cure for type 1 diabetes (T1D). Through the acquisition, Vertex plans to advance its potentially curative VX-880 programmes in T1D.

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Trending Sources

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Updated Recombinant Zoster Vaccine Recommendations Accepted by Physicians, but Knowledge Gaps, Financial Barriers Persist

Pharmacy Times

Though most primary care physicians indicate a willingness to accept expanded recommendations from the Advisory Committee on Immunization Practice suggesting administration of recombinant zoster vaccine for adult patients who are immunocompromised, cost concerns and knowledge gaps limit vaccine delivery.

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Beyond the pill in an outcomes-based world

pharmaphorum

Going beyond the pill is proving to be a win/win for patients and pharma alike – because improved outcomes are better for everyone. With growing numbers of people around the world living with long-term conditions, the pharmaceutical industry has a golden opportunity to use its expertise to truly enhance lives. But innovative new products are only part of the equation, because even the most efficacious drugs will only work as part of a holistic programme of care that includes mental health suppor

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pediatric Hepatitis Levels Remain Consistent With Pre-Pandemic Levels

Pharmacy Times

Hepatitis-associated emergency department visits and hospitalizations, liver transplantations, and adenovirus stool testing results in pediatric patients were not found to increase during the COVID-19 pandemic.

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ViiV, Roche and Pfizer top in ESG, according to patients

European Pharmaceutical Review

According to a recent survey of patient groups, Roche, Pfizer, ViiV Healthcare and Gilead Sciences are among the top companies for implementing and reporting progress on environmental, social, governance (ESG) activities. However the survey of 1,500 patient groups also found that 55 percent were not aware of pharma’s ESG programmes, suggesting pharma needs to better include and consider the patient perspective in establishing their ESG goals.

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Ensuring adequate sanitisation: disinfectant-resistant microbes in cleanrooms

European Pharmaceutical Review

Microbes developing resistance to disinfectants is a major emerging problem in pharmaceutical manufacturing cleanrooms and, if left unchecked, could present a threat to drug quality and, therefore, human health. More than 480 warning letters solely related to the failure to produce aseptic conditions because of deficient cleaning and disinfection systems for cleanrooms and their equipment, were issued by regulators between 2013 to 2018.

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Expert: Building Resilience Can Help Dismantle Structural Racism Within Health Systems

Pharmacy Times

Vibhuti Arya Amirfar, PharmD, MPH, discusses building individual and systems resilience to dismantle structural racism in the pharmacy field.

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AstraZeneca to acquire TeneoTwo and its blood-cancer therapeutic

European Pharmaceutical Review

AstraZeneca will acquire all outstanding equity of TeneoTwo for an upfront payment of $100 million on closing. The pharmaceutical giant will make further milestone-related payments of up to $805 million related to R&D and up to $360 million on achievement of commercial milestones. The acquisition of TNB-486 further diversifies AstraZeneca’s haematology pipeline, which spans multiple therapeutic modalities and mechanisms to address a broad spectrum of blood cancers.

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Augmented Intelligence Tool Helps Ensure Timely Referrals to Palliative Care for Patients With Advanced Cancer

Pharmacy Times

An intelligence-based system could help improve the timeliness of referrals to palliative care and hospice services in a community oncology environment.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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FACTOR AFFECTING ON THE DANDRUFF GROWTH AND THE IMPACT OF NATURAL HERBS AS AN ANTI-DANDRUFF AGENT

Pharma Tutor

FACTOR AFFECTING ON THE DANDRUFF GROWTH AND THE IMPACT OF NATURAL HERBS AS AN ANTI-DANDRUFF AGENT. About Authors. Avdesh Thassu. MPharm.(Nat. Chem.); MBA (Mkt.). Associate Vice President. Global Regulatory Affairs, Emami Limited, 7044455199. athassu@hotmail.com. Chandra Mohan Nandi. MSc.(Med. Chem.). Deputy Manager, Global Regulatory Affairs, Emami Limited, 9051706947. chandramohannandi@yahoo.in. admin.

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Treating Patients with Diabetes Using a Comprehensive Patient Care Plan

Pharmacy Times

The American Diabetes Association guidelines have self-care and lifestyle recommendations for patients and health care professionals.

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COVID won't evolve to become 'less deadly' — and RedHill is prepping for the long haul

PharmaVoice

RedHill Biopharma’s chief operating officer, Guy Goldberg, says the company’s oral COVID-19 therapy could still be needed on a global scale.

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Younger Eligible Adults Are Less Likely to Meet Recommended Colorectal Cancer Guidelines

Pharmacy Times

Screening participation increased over time, but the increase was smallest among individuals aged 50 to 54.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Lymphoma Research Foundation awards $5.7m to pursue blood cancer treatments

Outsourcing Pharma

The organization has given 29 research grants to scientists representing 17 different US institutions pursuing lymphoma treatments and cures in their work.

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Digital health financing falls to two-year low in first half

pharmaphorum

The buoyant financing environment for digital health companies that took off during the pandemic looks like it has come to an end, according to new figures from market watcher Rock Health. The influx of cash that flowed into the sector during the COVID-19 crisis has been followed by a correction that emerged in the first quarter of 2022 and deepened in the second quarter, according to its latest report.

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Daily Medication Pearl: Rucaparib (Rubraca)

Pharmacy Times

Rucaparib (Rubraca) is a poly (ADP-ribose) polymerase (PARP) inhibitor used for ovarian cancer, fallopian tube cancer, primary peritoneal cancer, and castration-resistant prostate cancer.

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Health Canada to review Arcutis’ roflumilast cream NDS for plaque psoriasis

Pharmaceutical Technology

Health Canada has accepted to review Arcutis Biotherapeutics’ New Drug Submission (NDS) for roflumilast cream 0.3% (ARQ-151) to treat plaque psoriasis in adult and adolescent patients. The Roflumilast cream is a once-a-day topical formulation of the selective phosphodiesterase type 4 (PDE4) inhibitor, roflumilast. A validated target in dermatology, PDE4 is an enzyme that induces overactive immune responses.

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How The Pandemic Has Changed Discussions of Wellness, Mental Health Among Hematology-Oncology Pharmacists

Pharmacy Times

Experts discuss tools and trainings that health care institutions have established during the pandemic to support hematology-oncology pharmacists who are struggling with wellness and mental health challenges.

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US to procure 3.2 million doses of Covid-19 vaccine from Novavax

Pharmaceutical Technology

Novavax has signed an agreement with the US Department of Health and Human Services (HHS), in partnership with the Department of Defense, under which the US government will procure 3.2 million doses of the company’s Covid-19 vaccine, NVX-CoV2373, in the initial stage. The order is contingent on the vaccine obtaining Emergency Use Authorization (EUA) from the US Food and Drug Administration (FDA) as well as the Centers for Disease Control and Prevention (CDC) recommendation.

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Toxicity Management of BTK Inhibitors

Pharmacy Times

Experts navigate MCL drug interactions, including those between BTK inhibitors with common anticoagulants and antifungals.

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Here are the 2022 BoardVitals Dental School Scholarship Winners 

Board Vitals - Pharmacist

As technology develops and knowledge progresses, the medical industry sees advancements that improve the quality of care offered to patients. These advancements cover all areas of healthcare, including dentistry. In an effort to support the dentists of the future, BoardVitals launched their first Dental School Scholarship this year. For the 2022 BoardVitals Dental School Scholarship , we asked current dental students to answer the prompt: “In what area do you think the next major advancement in

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Understanding The Prevalence of Mutations in Treatment of MCL

Pharmacy Times

Drs Jain and Wang discuss concerns regarding mutations in the treatment setting for patients with mantle cell lymphoma.

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Forecasters Weigh In: What’s Next for Commercial Forecasting?

PharmExec

Now Available On Demand! What is key learning? Over 50% of industry forecasters said they would like better access to one key thing. Join us to discuss this important finding and more from our IQVIA Commercial Forecasting Trends Survey.

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Clinical Overview: Glucarpidase (Voraxaze) for Methotrexate Toxicity

Pharmacy Times

Methotrexate is an immunosuppressive agent used to treat cancer, dermatology-, and rheumatology-related issues.

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Acute lymphocytic leukaemia leads in cell therapy clinical development

Pharmaceutical Technology

The success of chimeric antigen receptor T-cells (CAR-T) in blood cancers has led to the US Food and Drug Administration's (FDA) approval of six products with a pipeline of cell therapies that numbers in the thousands. An analysis of GlobalData’s Pharma Intelligence Centre for cell therapies in major oncology indications in the eight major markets (8MM: the US, France, Germany, Italy, Spain, the UK, Japan and China) suggests that acute lymphocytic leukaemia (ALL) dominates that pipeline, with mo

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Innoviva builds in infectious diseases with La Jolla Pharma buy

pharmaphorum

La Jolla Pharmaceuticals’ dreams of building a lucrative business from its stable of drugs used in infectious diseases never really paid off, and the company has now sold itself to royalty and asset management firm Innoviva in a deal valued at $149 million. The deal centres on La Jolla’s lead product Giapreza (angiotensin II), used to increase blood pressure in adults with septic shock, and antibiotic Xerava (eravacycline) for complicated intra-abdominal infections (cIAIs), approved

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Filings buzz in pharmaceuticals: 38% decrease in digitalization mentions in Q2 of 2022

Pharmaceutical Technology

Mentions of digitalization within the filings of companies in the pharmaceutical industry fell 38% between the first and second quarters of 2022. In total, the frequency of sentences related to digitalization between July 2021 and June 2022 was 400% higher than in 2016 when GlobalData, from whom our data for this article is taken, first began to track the key issues referred to in company filings.

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NIH starts trial of Moderna’s mRNA Nipah virus vaccine

pharmaphorum

Researchers in the US have started a clinical trial of a vaccine against Nipah virus, a serious infection caught from animals that has a fatality rate of between 40% and 70%, developed by mRNA specialist Moderna. Nipah is one of the pathogens that Moderna has identified as the targets of its global public health strategy , an initiative aimed at developing vaccines for 15 infectious diseases that pose the biggest public health risk worldwide.

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Daily OTC Pearl: Instant Sleep

Pharmacy Times

Instant Sleep is intended to aid with falling asleep faster and staying asleep longer.

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PCI Pharma Services Inks Supply Chain Digitization Deal

Pharmaceutical Commerce

Partnership with Thoughtworks expected to increase transparency, streamline processes.

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Q&A With Stanford Business School Professor and Harvard Business School Visiting Professor Jeffrey Pfeffer

PharmExec

Pfeffer discusses his seven rules for power.

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Wacker to Begin Building mRNA Actives Competence Center

Pharmaceutical Commerce

Production capacity for the contract manufacturer is expected to more than triple.

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VisionHealth and Boehringer Ingelheim link up for asthma

Pharma Times

The partnership will deliver digital therapy support for asthma and COPD patients

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