Wed.Nov 30, 2022

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What they are saying: PASTEUR Act can help fight antimicrobial resistance

PhRMA

Antimicrobial resistance (AMR) is a growing health crisis resulting in nearly 50,000 U.S. deaths each year and 1.27 million globally on an annual basis – higher than HIV/AIDS and malaria. To slow and control continued AMR, we need a robust pipeline of novel products, and at the same time we need to ensure they are used only in a limited set of circumstances and in only the most necessary cases.

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Dextromethorphan Found Ineffective for Medication Abortion Pain Management

Drug Topics

Results from a randomized controlled trial study suggest dextromethorphan may even worsen patient pain experience.

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Trending Sources

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Study Explores Challenges in Uptake of Long-Acting Injectable PrEP

Pharmacy Times

Challenges for uptake of long-acting injectable pre-exposure prophylaxis in populations at risk for HIV include fear of needles, potential adverse effects, and concerns about diminished efficacy.

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Recession Ahead: How to Prepare Your Pharmacy

Drug Topics

Many independent pharmacies closed during the last recession.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Experts Review Updates on the Public Health Strategy for Monkeypox

Pharmacy Times

Although it has received less attention as flu season begins, public health experts are continuing to urge vaccination against monkeypox.

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Stanford is investigating its president over allegations of research misconduct

STAT

Stanford University has opened an investigation into its president, Marc Tessier-Lavigne, a renowned neuroscientist and former biotech executive, for research misconduct after experts alleged papers on which he was an author included altered images, the university confirmed. The university’s board will oversee the investigation.

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More Trending

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Elon Musk says Neuralink’s brain-machine interface could enter human studies next year

STAT

Elon Musk’s brain-machine interface company Neuralink aims to put its first implant in a human subject in the next six months, he said during an event Wednesday. Musk said the company has been “working hard to be ready for our first human,” and has submitted most of the required paperwork to the Food and Drug Administration to launch a study in humans.

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Anticipated Developments on the Horizon for Patients With HR+/HER2- Breast Cancer

Pharmacy Times

Expert panelists discuss potential coming developments in the treatment landscape for breast cancer.

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FDA approves first microbiome drug from Ferring Pharmaceuticals

STAT

The Food and Drug Administration approved the first therapy using bacteria from stool samples to treat a bowel disorder on Wednesday, paving the way for several similar treatments in development.  The drug, called Rebyota, is given as a one-dose treatment for clostridium difficile infection s, commonly known as C. diff., in which the toxin-producing bacteria disrupts the normal balance in a person’s digestive system.

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5 Key Sessions and Interviews at the American Society of Health-System Pharmacists 2022 Midyear Clinical Meeting

Pharmacy Times

Pharmacy Times will be covering the American Society of Health-System Pharmacists 2022 Midyear Clinical Meeting from December 4 to 8.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Covid evolution wipes out another antibody treatment, threatening the country’s medicine cabinet

STAT

The Food and Drug Administration on Wednesday ended its emergency authorization for the only remaining Covid-19 antibody therapy cleared for use, saying variants that render it ineffective are now dominant in the United States. The news about bebtelovimab makes official what has been anticipated for several weeks, as the Omicron sublineages BQ.1 and BQ.1.1 have been growing in prevalence.

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OTC Product News: November

Pharmacy Times

This months over-the-counter (OTC) product guide highlights products that contain natural ingredients.

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STAT+: On the long road to treating Huntington’s genetic stutter, scientists return to overlooked clues

STAT

In the spring of 1981, a geneticist from Indianapolis and a neurologist from Chicago got in a car and for three days they crisscrossed the yellowing cornfields of Iowa. Every now and then, they stopped at a house to draw blood from the inhabitants — more than 30 members of one extended family spread across the state. The scientists sent the blood 950 miles east to Massachusetts General Hospital in Boston, to a tiny lab (recently converted from a storeroom) where a 28-year-old postdoc name

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Study Finds Attachment Anxiety Can Lead to False Memories

Pharmacy Times

Adults with attachment anxiety were more likely to misremember facts when they could see the person speaking.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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‘This actually changes everything’: Altered image in 1999 paper raises potential peril for Stanford president

STAT

New findings of altered images in research co-authored by Stanford University president Marc Tessier-Lavigne add to the weight of allegations against him, according to experts on research misconduct. On Tuesday, Stanford announced an investigation into its president following allegations of altered images in four papers co-authored by Tessier-Lavigne over a seven-year period earlier in his research career.

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Current pipeline developments could bring new hope for patients with PPMS

Pharmaceutical Technology

Multiple sclerosis (MS) is an autoimmune disease causing chronic inflammation and demyelination of the nerves, affecting around 2.5 million people worldwide. While patients diagnosed with relapsing MS (RMS) have a wide range of marketed treatment options, patients diagnosed with progressive MS, especially primary progressive MS (PPMS), have very limited treatment options.

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Opinion: Better lab test standards can ensure precision medicine is truly precise

STAT

Cancer is becoming less deadly in America. According to the recently released Annual Report to the Nation on the Status of Cancer , overall cancer death rates have continued to decline by about 2% per year over the last several years for Americans of all ages, races, and genders. The decline in cancer death rates is clearly welcome news and coincides with a significant shift in cancer treatment through the development of new targeted therapies and accompanying diagnostic tests that guide their u

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Veeva Systems Summit, Madrid – pharmaphorum reflects

pharmaphorum

Veeva Systems invited pharmaphorum to attend its industry summit in Madrid this week, a huge event that gathered together over 1,000 individuals from life sciences and pharma. The Marriot Auditorium & Conference Centre was the venue for this occasion, the largest global conference of its kind in Europe, the titular space made clear just how ‘big’ these systems are in facilitating what pharma does, today and very much tomorrow.

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Opinion: Excise taxes on tobacco, alcohol, and sugary beverages benefit health and public budgets

STAT

The Covid-19 pandemic blew up budget deficits in low- and middle-income countries, pushing many toward or into precarious financial straits. There is also growing pressure on policymakers to soften the impact of food and energy inflation with temporary tax and tariff cuts and consumption subsidies, measures that will need to be offset by other fiscal responses to fill budget holes.

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Amid 'tripledemic,' text-based pediatric care startup Summer Health extends free trials to parents

Fierce Healthcare

Amid 'tripledemic,' text-based pediatric care startup Summer Health extends free trials to parents. agliadkovskaya. Wed, 11/30/2022 - 15:30.

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With no exit strategy from ‘zero Covid’ policy, China could face tsunami in cases, experts fear

STAT

As the world watches the rare spectacle of protesters challenging China’s authoritarian leadership over its increasingly perplexing “zero Covid” policy, people who study the disease see threats ahead for China — and beyond. The zero Covid policy, which has kept cases and deaths in China to negligible numbers throughout the pandemic, seems doomed to fail in the face of the highly transmissible Omicron variant of the SARS-CoV-2 virus, they believe.

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Mental health providers decry 'mind-numbing' prior authorization burdens as Senate debates reforms

Fierce Healthcare

Mental health providers decry 'mind-numbing' prior authorization burdens as Senate debates reforms. rking. Wed, 11/30/2022 - 13:13.

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STAT+: ‘This actually changes everything’: Altered image in 1999 paper raises potential peril for Stanford president

STAT

New findings of altered images in research co-authored by Stanford University president Marc Tessier-Lavigne add to the weight of allegations against him, according to experts on research misconduct. On Tuesday, Stanford announced an investigation into its president following allegations of altered images in four papers co-authored by Tessier-Lavigne over a seven-year period earlier in his research career.

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How tech companies are using AI to tackle clinician burnout, administrative burdens

Fierce Healthcare

How tech companies are using AI to tackle clinician burnout, administrative burdens. aburky. Wed, 11/30/2022 - 14:21.

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CDC launches initiative to test wastewater for polioviruses in some communities

STAT

With growing concern about the circulation of vaccine-derived polioviruses in the United States, the Centers for Disease Control and Prevention said Wednesday that it would work with select communities across the country to conduct wastewater surveillance for the viruses. The launch of the initiative follows the discovery over the summer of vaccine-derived polioviruses circulating in the sewage of a number of counties in and around New York City.

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Invest in pharmacists to improve patient outcomes

Drug Store News

To best address social determinants of health and improve the health of low-income. patients, start with pharmacists.

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STAT+: Roche’s failed Alzheimer’s studies lend weight to an emerging idea about potential treatments

STAT

SAN FRANCISCO — The failure of a once-promising Alzheimer’s disease medicine from Roche appears to have a simple explanation: The drug didn’t do its job. In a presentation just weeks after Roche announced the drug’s failure , the Swiss pharma giant on Wednesday said its treatment had a disappointing effect on a toxic protein called amyloid, whose accumulation in the brain is thought to drive the advance of Alzheimer’s.

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Texas hospitals warn of rural closures, care delays and service cuts without legislative support

Fierce Healthcare

Texas hospitals warn of rural closures, care delays and service cuts without legislative support. dmuoio. Wed, 11/30/2022 - 16:50.

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‘The more voice, the better’: How tech could bring a fuller picture of living with a disability to health records

STAT

Electronic health records don’t leave much room for nuance: On paper, two patients with the same type of knee problem might score the same on a standardized walking test, and have tried the same treatment options. But once they walk out of the clinic, the same condition could impact each of their lives in considerably different ways. “If disability is an interaction between a person’s health condition, and their environment, and the personal choices they make, we’ve g

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Viatris, Biocon Biologics complete biosimilars transaction

Drug Store News

Upon the completion of a transition services agreement, Biocon Biologics will assume responsibility for commercial, regulatory and other related services.

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NEJM publishes lecanemab Alzheimer’s study results

European Pharmaceutical Review

Full study results on Eisai’s pivotal Phase III Alzheimer’s (AD) trial for lecanemab, an anti-amyloid beta (A?) protofibril antibody , suggest that the drug could slow the rate of disease progression by 2.5-3.1 years and help people remain in the earlier stages of the disease for longer. The data has been published in The New England Journal of Medicine (NEJM) and was presented at the 2022 Clinical Trials on Alzheimer’s Disease (CTAD) conference in the US.

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World AIDS Day Raises Awareness of Disparities, Barriers to HIV Care

Pharmacy Times

The 2022 theme is “Putting Ourselves to the Test: Achieving Equity to End HIV.”.

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Ariana Grande channels Mod era in fragrance duo

Drug Store News

Mod Vanilla and Mod Blush fragrances were inspired by the modernity, freedom of expression and individuality of the 1960s London subculture.

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Study comparing surgical masks to N95s stirs controversy

Fierce Healthcare

Study comparing surgical masks to N95s stirs controversy. fdiamond. Wed, 11/30/2022 - 15:58.

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