Mon.Sep 26, 2022

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Monkeypox in Populations Presenting with Neurologic Syndromes Require Diagnosis

Pharmacy Times

Included in the literature review were the known neurologic complications of smallpox, including encephalitis, transverse myelitis, and acute disseminated encephalomyelitis.

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STAT+: Biotech turns to new and strange viruses to overcome gene therapy’s limitations

STAT

CAMBRIDGE, Mass. — The fluorescent orange sticker atop the white machine reads “BIOHAZARD,” but it’s a bit of a misnomer. Although Earth abounds with pathogens that can maim, kill, paralyze, and poison, the specimens inside this machine — being pipetted left and right behind glass for sequencing — are probably the most innocuous human viruses you will ever encounter.

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Trending Sources

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Culturally Competent Care is a Large Part of Pharmacy Care, Deepening Community Connections

Pharmacy Times

Students from the Daniel K. Inouye College of Pharmacy at the University of Hawaii discuss the importance of culturally competent care in Hawaii.

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Opinion: Subject, not suspect: The new hazards of conducting clinical research in the Dobbs era

STAT

Here’s a scenario anyone who has done clinical research will recognize: A 32-year-old woman participating in a Phase 1 healthy-volunteer crossover clinical trial tested negative for pregnancy when she enrolled and agreed to use contraception during the course of the trial, as specified in the protocol. After completing the first phase of the trial, she checked in for the second phase, at which time the required pregnancy test was positive.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study Suggests Moral Values Predict Regional Differences in COVID-19 Vaccination Rates

Pharmacy Times

The data showed moral concerns about fairness, loyalty, and purity influenced county-level vaccination rates, but care and authority did not.

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Influencer Marketing and Social Health: Optimizing Pharma’s Impact

pharmaphorum

Social health—the dynamic, real-time action people take to find meaningful connections and share information that impact the health journey—has dramatically shifted the ways in which healthcare marketers can, and should, reach their desired audiences. . Through Health Union’s unique and expansive Social Health Network of more than 100,000 patient leaders; and millions of engaged patients and caregivers across a growing portfolio of more than 40 condition specific online health communities, this

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More Trending

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Pfizer, Sangamo resume haemophilia gene therapy trial

pharmaphorum

Pfizer and Sangamo have restarted recruitment of patients into their registration trial for haemophilia A gene therapy giroctocogene fitelparvovec, after the FDA lifted a clinical hold on the study. The phase 3 AFFINE trial was paused voluntarily by the two partners almost a year ago, and subsequently placed on hold by the FDA, after patients treated with the therapy produced higher than expected levels of Factor VIII – the clotting factor that giroctocogene fitelparvovec is designed to produce

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STAT+: Health insurers are painting a misleading picture of Medicare Advantage savings, experts say

STAT

The health insurance industry is continuing its campaign to convince the public that Medicare Advantage saves taxpayers money, but experts say federal data still concludes the exact opposite — and that the program as currently designed is a drain on Medicare’s trust fund. America’s Health Insurance Plans, the industry’s primary lobbying group, funded a new report that was conducted by actuaries at Wakely Consulting Group.

Insurance 101
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Walmart, Claire’s broaden fashion accessory, jewelry availability

Drug Store News

Claire’s fashion accessories and jewelry are now available at more than 2,500 Walmart locations nationwide, online, and at more than 36 Claire’s stores-in-stores within Walmart.

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Opinion: FDA: Ignore a pharma company’s deceptive racial equity argument for keeping Makena, an ineffective preterm labor drug

STAT

In an effort to sway the Food and Drug Administration not to withdraw accelerated approval of Makena, a drug developed to prevent preterm birth that does no such thing, a pharmaceutical company owned by a private equity company is making the specious argument that the drug should be kept on the market because it may — the emphasis is mine — work in Black people.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Health Experts’ Predictions for the 2022 Flu Season

BuzzRx

Recent flu seasons over the past couple of years have been unpredictable due to the COVID-19 pandemic. Measures such as school closures, work from home, lockdowns, wearing masks, and social distancing have affected the seasonal flu, with fewer cases in general. However, now that life is pretty much back to normal in 2022, things might be different. So, what are public health experts predicting for the coming influenza season?

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Daiichi Sankyo grabs first approval for blood cancer drug Ezharmia

pharmaphorum

Japan’s Daiichi Sankyo has claimed its first worldwide approval for Ezharmia, a first-in-class dual EZH1 and EZH2 inhibitor for the treatment of patients with relapsed or refractory adult T-cell leukaemia/lymphoma (ATL). The Ministry of Health, Labour and Welfare (MHLW) in Japan has cleared Ezharmia (valemetostat tosylate) based on the results of an open-label phase 2 trial which revealed a 48% overall response rate with the drug in previously-treated ATL patients.

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STAT+: Some European regulators are starting to take steps to ensure clinical trial results are reported

STAT

Regulators in half a dozen European countries are now taking steps to enforce requirements that clinical trial sponsors make study results public, although three other countries have so far taken little to no action, a new analysis finds. Specifically, Austria, Belgium, Denmark, Finland, Germany, Sweden and the Netherlands are in varying stages of prompting sponsors to publicize results of their past clinical trials.

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Mitigate Risk for Errors Involving Paxlovid

Pharmacy Times

Take steps to safeguard prescribing, dispensing, and patient use of the COVID-19 antiviral medication.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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GM herpes virus fights advanced cancers

European Pharmaceutical Review

At the 2022 European Society for Medical Oncology Congress (ESMO) conference, promising results from a Phase I trial, suggesting that a novel genetically modified (GM) herpes virus eradicated or reduced advanced cancers, were presented. The GM herpes simplex virus (RP2) successfully treated twenty five percent of patients with different advanced cancers, including skin, oesophageal and head and neck cancers.

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3 keys to value for unlocking the promise of cell therapies

PharmaVoice

There is no question about the incredible clinical impact cell therapies can have on the lives of patients. However, this impact is the result of innovation that does not equate to a simple, straightforward commercialization process.

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STAT+: Pharmalittle: GSK picks its first female CFO; Pfizer advances Omicron booster for kids

STAT

Good morning, everyone. Damian Garde here, filling in for Ed Silverman at the outset of yet another working week. Here’s hoping the travails of your day tend toward the painless. Below are a few items to get you started, and, as always, if you hear something curious, do let us know. … GSK appointed Julie Brown, formerly of Burberry, to serve as its chief financial officer, the company’s first female CFO, Bloomberg tells us.

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HOPA Provides Plan to Address Oncology Drug Shortages

Pharmacy Times

Experts discuss insight from a recently published oncology drug shortages research project and HOPA’s plan to address related issues based on the project’s findings.

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BJ’s Wholesale Club to open 1st Indiana store

Drug Store News

Located in Noblesville, Ind., the store will open on Sept. 30, bringing its total number of locations in the United States to 231, the warehouse club chain said.

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Pharmacy Focus: Oncology Edition - Experts See Promising Future for the Treatment of Acute Lymphoblastic Leukemia

Pharmacy Times

CAR T therapies are potentially revolutionizing the treatment of acute lymphoblastic leukemia (ALL).

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Schnucks kicks off donation campaign supporting United Way of Greater St. Louis

Drug Store News

Donations collected will be used to support the organization’s mission of mobilizing the power of communities to help people live their best possible lives.

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Pfizer strengthens AI drug discovery collaboration with equity investment

Outsourcing Pharma

Pfizer and CytoReason have been partnered on artificial intelligence and machine learning technologies for drug discovery and development since 2019. The latest deal brings the companies closer.

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AbbVie Cork facility €60 million expansion

European Pharmaceutical Review

AbbVie , an international R&D biopharmaceutical enterprise has celebrated its 20th anniversary by investing in extensive renovations at its manufacturing site in Cork, Ireland. The €60 million expansion will open 70 new jobs in sterile manufacturing, quality control and engineering in 2025. Construction at the Carrigtwohill facility built in 2013 is set to begin in 2023. “This latest investment is a fantastic opportunity for the Cork site and a recognition of the expertise and commitme

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Food Lion expands grocery pickup service to 24 additional stores

Drug Store News

Food Lion To Go, beginning Sept. 26, will service customers in 24 additional stores throughout North Carolina and Kentucky.

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OTC Products: September 2022

Pharmacy Times

This month's OTC product news features Hiccupops, deep relief acne treatment, and lidocaine patches.

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CVS Pharmacy, FARE partner for a safe 2022 Halloween

Drug Store News

CVS Pharmacy and FARE are working together to help create a more inclusive and safe Halloween for all kids with food allergies.

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Pfizer, BioNTech Submit Application for EUA of Omicron Bivalent Booster in Children Aged 5 Through 11

Pharmacy Times

Pfizer and BioNTech have also initiated a phase 1/2/3 study evaluating the safety, tolerability, and immunogenicity of different doses and dosing regimens with the vaccine in children.

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Pfizer 20vPnC vaccine as safe as Prevenar 13®

European Pharmaceutical Review

Positive top-line Phase III study results from Pfizer’s major 20-Valent Pneumococcal Conjugate Vaccine (20vPnC) indicate that it could help prevent invasive pneumococcal disease (IPD) and pneumonia. The trial, conducted with 4,700 infants and 800 toddlers and children of all ages ( NCT04546425 ), measured the vaccine’s immunogenicity and safety parameters against Prevenar 13 ® , a common paediatric vaccine.

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Co-Infected HIV, Hepatitis C Patients May Have Increased Risk of Heart Attack

Pharmacy Times

Research suggests that an HIV patient’s risk of heart attack increases with each passing decade, and this risk is nearly 3-fold among patients with HIV who are also positive for hepatitis C.

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Medicines for migraines, reflux and cancer to become cheaper in Australia

The Guardian - Pharmaceutical Industry

Changes to the Pharmaceutical Benefits Scheme expected to save Australians $130m per year, federal government says Follow our Australia news live blog for the latest updates Get our free news app , morning email briefing or daily news podcast Medicines for migraines, stomach ulcers and other conditions will become cheaper next month as the Albanese government adds new treatments to the Pharmaceutical Benefits Scheme.

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Ultomiris for generalised myasthenia gravis

European Pharmaceutical Review

The European Commission (EC) has granted adult patients with anti-acetylcholine receptor (AChR) antibody-positive generalised myasthenia gravis (gMG), a treatment-first with the drug Ultomiris (ravulizumab). With Ultomiris patients only require a treatment dose every eight weeks. gMG is a rare autoimmune disorder which causes reduced muscle function and atrophy.

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PQA Appoints 15 Individuals to Serve on COPD Treatment Ratio TEP

PQA

PQA has appointed 15 individuals from member organizations to serve on a technical expert panel (TEP) to review and provide input on draft specification for a health plan performance measure concept: COPD (chronic obstructive pulmonary disease) Treatment Ratio (CTR). The COPD Treatment Ratio TEP will provide expert input on the concept, which will assess the percentage of individuals whose CTR was?

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Peli BioThermal Introduces Tokyo Service Center

Pharmaceutical Commerce

New facility will focus on company’s temperature-controlled pallet shipper rental program.

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Is There a Link Between COVID-19 and Increased Type 1 Diabetes Diagnoses?

Drug Topics

Two new studies offer conflicting results.

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