Sun.May 28, 2023

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Who’s acquiring who? Orphan designated drugs M&A activity in the pharmaceutical industry decreased by 23% in Q1 2023

Pharmaceutical Technology

Analysis of the key themes driving M&A activity reveals that orphan designated drugs accounted for 20 pharmaceutical deals announced in Q1 2023, worth a total value of $50.2bn. The $43bn acquisition of Seagen by Pfizer was the industry’s largest disclosed deal. GlobalData’s New Drug Approvals and Their Contract Manufacture report provides critical insight into the contract manufacturing organization (CMO) industry by analysing relative performance of major CMOs by number of drug

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How to Ease the Pain of a Sting

The People's Pharmacy

How do you ease the pain of an insect sting? We have heard from many readers about their favorite remedies to take the edge off after too close an encounter with a stinger. Some people make a paste of baking soda with water and apply that. We have also heard from numerous readers that a freshly cut onion put on the sting can help. Here is one reader’s take on that.

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AstraZeneca’s Ultomiris receives Japanese approval for NMOSD

Pharmaceutical Technology

AstraZeneca has received approval from the Japanese Ministry of Health, Labour and Welfare (MHLW) for its Ultomiris (ravulizumab) to prevent relapses in patients with neuromyelitis optica spectrum disorder (NMOSD), including neuromyelitis optica. The rare and debilitating autoimmune condition NMOSD affects the central nervous system (CNS), including optic nerves and the spine.

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Pickle Relish Will Do in a Pinch Against Leg Cramps

The People's Pharmacy

Over the years, we have collected quite a number of home remedies for sudden painful muscle cramps. Often these are leg cramps, but occasionally muscles in the hands or arms cramp as well. One favorite remedy that coaches love is pickle juice. A few sips of pickle juice can chase a cramp away. But what about pickle relish? Does it work as well? One reader says plain vinegar, without the pickles, works against nighttime leg cramps.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Who’s acquiring who? Immuno-oncology M&A activity in the pharmaceutical industry decreased by 8% in Q1 2023

Pharmaceutical Technology

Analysis of the key themes driving M&A activity reveals that immuno-oncology accounted for 12 pharmaceutical deals announced in Q1 2023, worth a total value of $43.4bn. The $43bn acquisition of Seagen by Pfizer was the industry’s largest disclosed deal. A detailed classification of therapy and technologies, regulatory and market access details and pipeline analysis for immuno-oncology are included in GlobalData’s Immuno-Oncology – Thematic Research report.

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Hypertension Pharmacology Crossword Puzzle

Med Ed 101

We have had a wonderful response to our previous pharmacology crossword on diabetes so I figured I try this again. With the help of a pharmacy student, Kevin Laspa, we have created a free hypertension pharmacology crossword puzzle! (ANSWERS AT THE BOTTOM OF THIS POST) I know some folks out there really like crossword puzzles, so I […] The post Hypertension Pharmacology Crossword Puzzle appeared first on Med Ed 101.

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BMS to Present P-III Study (COMMANDS) of Reblozyl (luspatercept-aamt) as 1L Treatment of Anemia in Adults with Lower-Risk MDS at ASCO and EHA 2023

PharmaShots

Shots: The P-III study evaluating Reblozyl vs epoetin alfa for anemia in 363 adult patients with very low, low, or intermediate-risk MDS who require RBC transfusions & are ESA-naïve with median treatment durations of 41.6 & 27wks. 58.5% vs 31.2% achieved the 1EPs of RBC-TI of 12wks. with Hb increase of 1.5g/dL within the first 24wks.; HI-E increase (74.1% vs 51.3%) @8wks. along with more durable responses with a m-DoR of RBC-TI ≥12wks. (126.6 vs 77wks.); RBC-TI (47.6% vs 29.2%) w

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Drug Digest: Advancements in the Implementation of Continuous Manufacturing

BioPharm

In this episode of Drug Digest, Pharmaceutical Technology editors discuss the advantages and savings that continuous manufacturing may offer as well as the very real obstacles that might make a fully continuous process not feasible, especially in biologics manufacturing.

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Prednisone Can Cause Anxiety, Depression and Insomnia

The People's Pharmacy

Corticosteroids are both a blessing and a curse. They can calm a serious allergic reaction and reduce inflammation. People with asthma may profit from a drug like prednisone during a flareup. Patients with autoimmune disease such as lupus, polymyalgia rheumatica or inflammatory bowel disease can also benefit at times from cortisone-type drugs. But prednisone can cause anxiety, depression and other psychiatric side effects.