an anthropomorphized red and blue pill illustrated in the style of the famous american gothic painting
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Ed Silverman, a senior writer and Pharmalot columnist at STAT, has been covering the pharmaceutical industry for nearly three decades. He is also the author of the morning Pharmalittle newsletter and the afternoon Pharmalot newsletter.

Rise and shine, everyone, another busy day is on the way. We can tell by the sudden presence of little ghouls and goblins walking past. No doubt, they are in search of the great pumpkin. We wish them luck, because you never know what you may find on that elusive quest. Of course, this calls for a cup of stimulation, and we are opening a new package of pecan pie for the occasion. What is upon us right now, however, is our ever-growing to-do list. Sound familiar? So here are some items of interest. Have a great day, everyone. …

All doses of Novo Nordisk’s blockbuster diabetes and obesity treatments are listed as available on the U.S. Food and Drug Administration drug shortage list as of Wednesday, raising the possibility that the medications could soon be taken off the list entirely, a development that could affect compounding pharmacies and patients relying on compounded drugs, STAT reports. Semaglutide, the scientific name for Novo’s GLP-1 diabetes drug Ozempic and obesity drug Wegovy, has been on the shortage list for over two years, with different doses being listed in shortage at various times. With all doses now listed as available, the FDA may soon pull it off the list, depending on its conversations with Novo about whether the company can sufficiently meet demand going forward.

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The number of layoffs in the U.S. pharmaceutical industry fell last month, although the number of job cuts remains well above what was seen at the same time in 2023, according to Challenger, Gray & Christmas, the outplacement and executive coaching firm. A total of 424 jobs were eliminated in October, far below the 3,073 positions that were cut in September. This was also well below the 1,624 jobs the industry slashed in October 2023. So far this year, pharmaceutical companies have axed a total of 12,751 positions, surpassing the 10,025 jobs that had been eliminated at the same time in 2023.

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