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How much is Jublia without insurance?

Jublia costs $1,032 without insurance or coupons, but there are ways to save
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By | Updated on Mar. 12, 2025 Medically reviewed by Leslie Greenberg, MD & Josephine Bawab, Pharm.D.

Key takeaways

  • Jublia is one of the most effective topical treatments for fungal toenail infections, but it is only currently available as a brand-name medication.

  • Oral antifungal treatment options, such as terbinafine, are effective, but they come with more side effects and drug interactions than topical treatments.

  • If Jublia is too expensive, consider enrolling in the manufacturer’s Rx Access Program, using a SingleCare coupon, or switching to a generic alternative.

In this article:

Jublia (efinaconazole) is a brand-name prescription drug that’s approved by the Food and Drug Administration (FDA) to treat fungal toenail infections (onychomycosis). As a 10% topical solution, Jublia is applied daily with an attached brush applicator to the affected toenails and surrounding skin for 48 weeks. Its active ingredient, efinaconazole, is an antifungal drug. In clinical trials, the drug cured the fungal infection in more than half of the participants. Although oral antifungals can be more effective at curing moderate-to-severe toenail fungus than Jublia, their side effects and drug interactions are more common and can sometimes, although rarely, be severe. Therefore, Jublia is a safer and easier alternative for many people and is one of the most effective topical therapies for toenail fungus. As such, it can be expensive without insurance or coupons, costing over $1,000 per month on average.

What is the generic for Jublia?

Jublia is only available as a brand-name drug. Topical efinaconazole, the active ingredient, will not have a generic version until 2035 due to its patent.

Is Jublia covered by insurance?

Insurance coverage for a Jublia prescription is spotty. Some health insurance and Medicare Part D drug plans provide coverage for Jublia, but many do not. If they do provide coverage, they may require healthcare providers to complete a prior authorization form before they consider approving it. Most insurance plans place Jublia in higher copay tiers, so the out-of-pocket cost may be higher than other toenail fungus prescription medications. Medicaid coverage for Jublia varies by state and plan. 

How much does Jublia cost without insurance?

Without health insurance coverage, a single applicator bottle containing 4 mL of Jublia 10% solution costs about $1,032 at the full cash price. How long that bottle lasts depends on how many toenails are affected and how well the medicine is applied. If 4 mL is enough for a 30-day supply, one year of Jublia treatment will cost over $12,000.

There are alternatives to Jublia that may be more affordable. Although the first-line treatment for mild toenail fungus includes over-the-counter (OTC) topical antifungal medications, they’re usually tried and failed before a healthcare provider prescribes a premium-priced drug like Jublia. For complicated cases of toenail fungus, the two effective alternatives are oral antifungals and specialty topical antifungals.

Oral antifungals are the most effective nail fungus treatments, but they can have significant side effects, with 13% of patients having headaches, 6% experiencing diarrhea, and 3% having elevated liver function tests. The first-line oral antifungal treatment is terbinafine tablets, with a 76% cure rate. The cost is about $260 for a 30-day supply, and it must be taken daily for 12 weeks to treat a toenail fungal infection. Terbinafine works in the nail for 30 weeks after the last dose.

Topical antifungals are often less successful than oral antifungals because of the thickness of the toenail. However, Jublia has one of the highest cure rates due to its ability to penetrate the nail effectively, but it may be expensive since it is only available as a brand-name medication. Generic topical treatment options include tavabarole and ciclopirox. 

One of the most effective ways to reduce the cost of Jublia is by using a SingleCare prescription discount card. The lowest SingleCare discount price for a 4 mL bottle of 10% Jublia solution is $670, compared with the average retail price of $1,032.
Drug name Price without insurance of brand-name drug  SingleCare price Savings options
Jublia (efinaconazole) $1,032 per 4 mL of 10% solution $670 per 4 mL of 10% solution of brand-name Jublia  See latest prices
Loprox

(ciclopirox)

 $151 per 6.6 mL of 8% solution of generic ciclopirox  $14 per 6.6 mL of 8% solution See latest prices
Kerydin

(tavaborole)

 $1,394 per 10 mL of 5% solution of generic tavaborole $43 per 10 mL of 5% solution See latest prices
Terbinafine $259 per 30, 250 mg tablets of generic terbinafine $11 per 30, 250 mg tablets See latest prices
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.

How to get Jublia without insurance

If you have health insurance but your policy doesn’t cover Jublia, you may be able to get Jublia at a discount by joining the manufacturer’s Rx Access Program. However, there are restrictions, and you’re ineligible if you don’t have commercial coverage. There are other ways to save, though. 

1. Get Jublia discounts with a SingleCare savings card

Instant discount prices on brand-name prescription drugs are available at participating pharmacies through SingleCare. For Jublia, visit SingleCare’s Jublia coupon page for available discounts. SingleCare’s lowest price for a 4 mL Jublia bottle is $670. 

2. Find the lowest price

Another way to unlock savings on brand-name drugs is to compare pharmacy prices. Comparing prices is easy using SingleCare’s Jublia average price history table. Find the best price at a local pharmacy near you.

3. Ask the prescriber about generic terbinafine

Nail fungus can sometimes be challenging to treat, so healthcare providers turn to established, more effective treatments like systemic (oral) antifungals. Terbinafine pills have the highest success rate at curing toenail fungus. The three-month regimen will cost about $780 at full retail price, $9,000 less than the 11-month Jublia regimen. Side effects and drug interactions could be a problem, so get medical advice from a healthcare provider before starting terbinafine.

4. Ask the prescriber about generic ciclopirox

If taking an antifungal pill is not an option, ask the prescriber about using topical tavaborole or ciclopirox. These are not as effective at curing toenail fungus as Jublia, but they are significantly less expensive.